OSU researchers find three-drug combo boosts immune system in stem cell transplantation

Healthy stem cells could turn into oral cancer, study finds

Researchers at University of California San Diego have discovered how healthy stem cells are transformed into cancer stem cells in the earliest stages of the disease. The study was published in Nature Communications.

February 07, 2025

Vol.51 No.05

Drugs & Targets

FDA approves Grafapex as preparative regiment for allogeneic hematopoietic stem cell transplantation in AML or MDS

FDA approved Grafapex (treosulfan), an alkylating agent, with fludarabine as a preparative regimen for allogeneic hematopoietic stem cell transplantation in adult and pediatric patients one year of age and older with acute myeloid leukemia or myelodysplastic syndrome on Jan. 22.

January 31, 2025

Vol.51 No.04

Clinical Roundup

UTSW scientists link hematopoietic cell transplant deaths to beta-blocker use

Patients can die if they take certain previously prescribed beta-blockers during a hematopoietic cell transplant due to suppressed signals from nerves that promote bone marrow regeneration, according to scientists at the Children’s Medical Center Research Institute at UT Southwestern, published in Cancer Discovery, builds upon previous CRI research by analyzing retrospective patient data to correlate beta-blocker use with significantly worse patient outcomes.

January 10, 2025

Vol.51 No.01

Clinical Roundup

Fralin Biomedical Research Institute spinoff company focuses on peptide drugs targeting cancer stem cells

Scientific progress often follows a prolonged path, but bioentrepreneur Samy Lamouille believes his dedication toward this pursuit will ultimately pay off for brain cancer patients.

November 22, 2024

Vol.50 No.44

Clinical Roundup

RAS-mutant leukemia stem cells behave differently from other leukemia stem cells

Research from the Icahn School of Medicine at Mount Sinai provides new insights into acute myeloid leukemia and its resistance to a common treatment. The study, published Oct. 30 in Nature, was led by Eirini Papapetrou, professor of oncological sciences at Icahn Mount Sinai. Acute myeloid leukemia is a devastating blood cancer that starts in...

November 08, 2024

Vol.50 No.42

Clinical Roundup

Mayo Clinic performs world’s first known successful total larynx transplant in a patient with active cancer

A multidisciplinary team of doctors at Mayo Clinic in Arizona performed the third known total larynx transplant in the U.S.

July 12, 2024

Vol.50 No.28

OSU researchers find three-drug combo boosts immune system in stem cell transplantation

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Healthy stem cells could turn into oral cancer, study finds

FDA approves Grafapex as preparative regiment for allogeneic hematopoietic stem cell transplantation in AML or MDS

UTSW scientists link hematopoietic cell transplant deaths to beta-blocker use

Fralin Biomedical Research Institute spinoff company focuses on peptide drugs targeting cancer stem cells

RAS-mutant leukemia stem cells behave differently from other leukemia stem cells

Mayo Clinic performs world’s first known successful total larynx transplant in a patient with active cancer

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