publication date: Nov. 29, 2016

NCI CTEP-Approved Trials for November

NCI CTEP approved the following clinical research studies last month. For further information, contact the principal investigator listed.


Phase I          9910

A Phase 1 Trial of MLN0128 (TAK-228) in Combination with Osimertinib (AZD9291) in Advanced EGFR Mutation Positive Non-Small Cell Lung Cancer (NSCLC) After Progression on a Previous EGFR Tyrosine Kinase Inhibitor 

University Health Network Princess Margaret

Cancer Center LAO

Bradbury, Penelope Ann

(416) 946-4522


Phase II         9775

A Phase 2 Study of MLN0128 (TAK-228) in Relapsed and/or Refractory Acute Lymphoblastic Leukemia (ALL)

Mayo Clinic Cancer Center LAO

Al-Kali, Aref

(507) 538-0591


Phase II         9780

A Phase 2 Study of MLN0128 (TAK-228) in Patients with Advanced Squamous Cell Lung Cancers Harboring NFE2L2 and KEAP 1 Mutations

Memorial Sloan Kettering Cancer Center

Paik, Paul K.

(212) 639-4013


Phase II         S1512

A Phase II and Pilot Trial of PD-1 Blockade with MK-3475 (Pembrolizumab) in Patients with Resectable or Unresectable Desmoplastic Melanoma (DM)


Continue reading CCL Nov 2016 – NCI CTEP-Approved Trials for November

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