High-Dose Chemo and Stem Cell Transplant Cures Most Relapsed Testis Cancer

Larry Einhorn reflects on his pioneering work on platinum-based chemotherapy at the AACI/CCAF annual meeting

When Larry Einhorn was a young physician in the early 1970s, actinomycin-D was the standard drug used to treat testicular cancer. It was—and still is—the most common carcinoma in young men ages 15-35.

November 22, 2024

Vol.50 No.44

By McKenzie Prillaman

Clinical Roundup

Genes that drive testicular cancer identified

In the largest sequencing study to date on testicular cancer, researchers at Children’s National Hospital have identified genes that contribute to testicular germ cell tumors (TGCT), the most common cancer among young, white men.

June 09, 2023

Vol.49 No.23

Clinical Roundup

Phase II study shows surgery is an effective alternative to chemo and radiation for early metastatic testicular cancer

Results of a multi-institutional clinical trial recently published in the Journal of Clinical Oncology show that surgically removing affected lymph nodes in the retroperitoneum of patients with early metastatic seminoma is an effective alternative to chemotherapy and radiation, with fewer long-term side effects.

March 31, 2023

Vol.49 No.13

Obituary

John Mark Cleland, first man to be cured of metastatic testicular cancer, dies at 71

John Mark Cleland died peacefully on Feb. 7, 2022, in Indianapolis. Some people reading this headline will have little or no idea who John Cleland was. However, if you are a medical or urological oncologist, you should. John Cleland was the first man whose metastatic testicular cancer was cured with combination chemotherapy containing cisplatin.

February 25, 2022

Vol.48 No.08

By Lawrence H. Einhorn and Daniel F. Hayes