The Cancer Letter

Inside information on cancer research and drug development

Clinical Roundup

Kadcyla produces OS benefit in HER2+ early-stage breast cancer with residual invasive disease after neoadjuvant treatment

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Long-term follow-up data from the phase III KATHERINE study in people with HER2-positive early-stage breast cancer who have residual invasive disease following neoadjuvant treatment showed that a statistically significant and clinically meaningful improvement in overall survival, a secondary endpoint, was observed with adjuvant Kadcyla (ado-trastuzumab emtansine) compared to Herceptin (trastuzumab).

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