The Cancer Letter

Inside information on cancer research and drug development

Clinical Roundup

Phase IIb study: mRNA-4157 (V940) in combination with Keytruda demonstrates improved survival in melanoma

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Adjuvant treatment with mRNA-4157 (V940), an investigational individualized neoantigen therapy (INT), in combination with Keytruda (pembrolizumab) demonstrated a statistically significant and clinically meaningful improvement in distant metastasis-free survival (DMFS) for patients with resected high-risk melanoma (stage III/IV) in a phase IIb study. 

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