Fox Chase researchers to use $497K NCI grant to develop platform for testing pancreatic cancer drug therapies

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Researchers at Fox Chase Cancer Center have received a $497,000 multi-year grant from NCI to develop a way to evaluate novel drug therapies in patients with pancreatic cancer.

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In a phase II clinical trial, a research team led by Nilofer Azad, professor of oncology and co-leader of the Kimmel Cancer Center’s Cancer Genetics and Epigenetics Program, and Marina Baretti, the Jiasheng Chair in Hepato-Biliary Cancer at the Kimmel Cancer Center, tested the safety and efficacy of the combination of two drugs: an immunotherapy, nivolumab, and an epigenetic drug, entinostat—a histone deacetylase inhibitor. 

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