Paired tumor-germline testing can enhance patient care—with guidance from genetics specialists

As cancer patients use AI chatbots, dangers lurk—but new safeguards can help

Patients affected by cancer are increasingly turning to artificial intelligence-powered chatbots, such as ChatGPT and Gemini, for answers to pressing health questions. These tools, available around the clock and free from geographic or scheduling constraints, are appealing when access to medical professionals is limited by financial, language, logistical, or emotional barriers.

June 27, 2025

Vol.51 No.25

By Ghulam Rasool, Brian D. Gonzalez and Katherine Chung-Bridges

Clinical Roundup

City of Hope launches AI tool to reduce burden of cancer care

City of Hope is using generative artificial intelligence to create operational efficiency, enable AI-driven patient personalization, improve access to clinical trials, and empower breakthrough research.

June 27, 2025

Vol.51 No.25

Clinical Trials & Tribulations

Optimizing dosing of expensive and toxic oncology drugs: Making America healthier

There is general agreement that the United States spends too much on health care, especially on pharmaceuticals. But what we spend on drugs is not simply a function of price. If eggs double in price, people can simply cut the number of eggs they eat in half. Simply stated, cost is the product of (price per unit times the number of units purchased).

June 20, 2025

Vol.51 No.24

By Mark J. Ratain, David A. Hyman, Jill E. Feldman, Beth R. Jacobson and Allen S. Lichter

In Brief

Samra Turajlić appointed director of Cancer Research UK Manchester Institute

Samra Turajlić was appointed the director of the Cancer Research UK Manchester Institute.

June 20, 2025

Vol.51 No.24

Clinical Roundup

Targeting Pol 1 could rewire cancer cells and suppress tumor growth, Johns Hopkins study finds

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.

June 20, 2025

Vol.51 No.24

Insights from ASCO 2025: Real-world evidence drives clinical decision-making

City of Hope researchers presented compelling real-world evidence and novel combination therapies at the 2025 ASCO Annual Meeting, with findings that could reshape treatment approaches for breast, colorectal, renal, and prostate cancers.

June 13, 2025

Vol.51 No.23

By City of Hope