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The Cancer Letter
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Clinical Roundup

Researchers identify novel molecular target for pancreatic cancer

Researchers at City of Hope have identified a new molecular target for treating pancreatic cancer, reports a Gastroenterologystudy published on April 8.
April 18, 2025
Vol.51 No.15
Clinical Roundup

Targeting FGFR2 may prevent or delay some KRAS-mutated pancreatic cancers

Precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma tumors harboring KRAS mutations had higher-than-normal expression of the FGFR2 protein, and FGFR2 inactivation delayed KRAS-mutated PDAC development in mice, according to results of a study published in Cancer Research, a journal of the American Association for Cancer Research.
April 04, 2025
Vol.51 No.13
Drugs & Targets

FDA approves cabozantinib for patients 12 and up with pNET and epNET

FDA approved cabozantinib (Cabometyx) for adult and pediatric patients 12 years of age and older with previously treated, unresectable, locally advanced or metastatic, well-differentiated pancreatic neuroendocrine tumors and well-differentiated extra-pancreatic neuroendocrine tumors.
March 28, 2025
Vol.51 No.12
Clinical Roundup

KRAS mutation is a significant predictor of metastasis and survival in pancreatic cancer, study shows

A new study by Mayo Clinic Comprehensive Cancer Center researchers found that the presence of a specific genetic mutation—KRAS circulating tumor DNA—strongly indicates a higher risk of cancer spread and worse survival rates for patients with pancreatic ductal adenocarcinoma. 
March 21, 2025
Vol.51 No.11
Clinical Roundup

Immunovia completes second clinical validation of next-gen pancreatic cancer test

Immunovia announced results from the VERIFI study, the second clinical validation study of its next-generation pancreatic cancer test. 
March 21, 2025
Vol.51 No.11
Funding Opportunities

The Stephenson Global Prize and Stephenson Global Scholar Grants calls for nominations, letters of intent

The Stephenson Global Pancreatic Cancer Research Institute, established to advance early detection, innovative treatments, and groundbreaking research for pancreatic cancer, has launched a call for nominations and Letters of Intent for two award opportunities.
March 14, 2025
Vol.51 No.10
Funding Opportunities

The Stephenson Global Pancreatic Cancer Research Institute creates Global Scientific Awards to advance pancreatic cancer research

The Stephenson Global Pancreatic Cancer Research Institute is creating new awards to advance pancreatic cancer research. 
February 14, 2025
Vol.51 No.06
Clinical Roundup

UCSD researchers identify enzyme that promotes pancreatic tumor growth and spread

Researchers at University of California San Diego School of Medicine have discovered that an enzyme called MICAL2 promotes tumor growth and spread in pancreatic ductal adenocarcinomas, the most common form of pancreatic cancer. 
January 10, 2025
Vol.51 No.01
Clinical Roundup

Cedars-Sinai to develop AI tool that predicts pancreatic cancer risk in Black patients

Cedars-Sinai investigators who previously developed an imaging tool that used artificial intelligence to predict pancreatic cancer are now working to adapt that tool specifically for Black patients, who have disproportionately high rates of the disease.
December 06, 2024
Vol.50 No.45
Drugs & Targets

FDA grants accelerated approval to zenocutuzumab-zbco for NSCLC and pancreatic adenocarcinoma

FDA has granted accelerated approval to zenocutuzumab-zbco (Bizengri) for adults
December 06, 2024
Vol.50 No.45

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