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The Cancer Letter
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Clinical Roundup

UNC study: Accurate diagnostic mammography outcomes vary by racial and ethnic groups

A multi-institutional study led by UNC Lineberger Comprehensive Cancer Center researchers found that diagnostic mammography results vary across racial and ethnic groups, with the rate of diagnostic accuracy highest in non-Hispanic white women and lowest in Hispanic women.
June 17, 2022
Vol.48 No.24
ASCO’s “rock concert” moments came 17 years apart—in 2005 and 2022
Guest Editorial

ASCO’s “rock concert” moments came 17 years apart—in 2005 and 2022
DESTINY-04 results extend HER2-targeted therapy to a larger population in breast cancer

The plenary session at the ASCO 2022 annual meeting saw that rarest of things at a scientific conference: a standing ovation. 
June 10, 2022
Vol.48 No.23
By George W. Sledge Jr.
Clinical Roundup

Lasofoxifene + abemaciclib shows potential in ER+/HER2− breast cancer with ESR1 mutation

Updated data have emerged from the ELAINE-2 clinical trial of lasofoxifene plus abemaciclib in women with locally advanced or metastatic ER+/HER2− breast cancer and an ESR1 mutation after progression on prior therapies. 
June 03, 2022
Vol.48 No.22
Drugs & Targets

FDA grants marketing authorization to Parsortix System for liquid biopsy in MBC

FDA granted marketing authorization to the Parsortix System for the harvesting of circulating cancer tumor cells in metastatic breast cancer.
May 27, 2022
Vol.48 No.21
In Brief

Priya Rastogi named CEO of NSABP Foundation

Priya Rastogi was named chief executive officer of the National Surgical Adjuvant Breast and Bowel Project Foundation, effective July 1. In addition to this new role, she will continue serving as medical director of NSABP. 
May 13, 2022
Vol.48 No.19
Clinical Roundup

Racial and ethnic disparities persist for early-stage breast cancer detection and survival

Breast cancer screening and early detection efforts have contributed to improved survival in recent decades, as breast cancer is more easily treated at early stages. But not all women have benefited equally. 
May 06, 2022
Vol.48 No.18
Drugs & Targets

Enhertu receives FDA approval for breast cancer indication

Enhertu (fam-trastuzumab deruxtecan-nxki) received FDA regular approval for adult patients with unresectable or metastatic HER2-positive breast cancer who have received a prior anti-HER2-based regimen either in the metastatic setting, or in the neoadjuvant or adjuvant setting and have developed disease recurrence during or within 6 months of completing therapy.
May 06, 2022
Vol.48 No.18
In Brief

Vera Bradley Foundation for Breast Cancer makes $12.5M commitment to IU School of Medicine

A gift commitment of $12.5 million to Indiana University School of Medicine from the Vera Bradley Foundation for Breast Cancer will support research in immunotherapy for triple negative breast cancer. 
April 22, 2022
Vol.48 No.16
Clinical Roundup

AURORA study identifies molecular features tied to breast cancer tumor spread

Susana Garcia-Recio, a research associate in the lab of Charles M. Perou at the UNC Lineberger Comprehensive Cancer Center, presented findings at the 2022 AACR annual meeting that identified molecular features responsible for the development and progression of metastatic breast cancer.
April 15, 2022
Vol.48 No.15
Drugs & Targets

FDA fast tracks targeted breast cancer immunotherapy Bria-IMT

FDA granted fast tack status to Bria-IMT for the treatment of metastatic breast cancer.
April 15, 2022
Vol.48 No.15

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