Vol.

No.

April 18, 2025Apr 18, 2025

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The Directors: Louis Weiner and Taofeek Owonikoko on keeping up morale amid uncertainty “We are resolute. We are committed to continuing to move the work forward.”

Cover Story

Podcast The Directors

The Directors: Louis Weiner and Taofeek Owonikoko on keeping up morale amid uncertainty

“We are resolute. We are committed to continuing to move the work forward.”

By Paul Goldberg

Speaking on The Cancer Letter Podcast, Taofeek Kunle Owonikoko recalled recent conversations with two junior faculty members at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center.

Trump administration seeks to slash NIH by roughly 40% as 27 institutes and centers are whittled down to eight
NCI to remain intact, but its finances are uncertain; FDA is spared big cuts

By Paul Goldberg

Regulatory News

RFK Jr. urges FDA staff to resist “agency capture” by special interests and resist “deep state”
Whistleblowers will be “honored”

By Jacquelyn Cobb

Clinical

TIL + pembro regimen achieves 24% response rate in solid epithelial tumors, marking a step forward in immunotherapy research

By Jacquelyn Cobb

Guest Editorial

What would Mary do?
Trump’s actions call for Lasker-style advocacy

By Kevin J. Cullen

City of Hope’s BMT program performs 20,000th transplant
49-year history creates 20,000 tomorrows

By Stephen J. Forman

Podcasts

In the Headlines: What’s in Trump’s draft budget?

Cancer Policy

NCI summarizes changes to the CCSG NOFO

John Burklow replaced by Seana Cranston as NIH chief of staff

Trump’s healthcare executive order could be a win for pharma

Trump administration says Harvard funding freezes will spare affiliated hospitals

In Brief

AACR announces 2025 Scientific Achievement Award recipients

Hope Rugo named director of City of Hope’s Women’s Cancers Program

USC Norris opens Keck Medicine of USC–Newport Beach Radiation Oncology and Imaging center

“1001 cuts,” a gynecologic oncologist’s award-winning documentary short, examines sexism in surgery

Clinical Roundup

American College of Radiology: “Americans shouldn’t forgo necessary, life-saving medical imaging”

Lung-MAP trial for NSCLC expands genomic screening options for patients

Disasters likely delay early cancer diagnoses, study shows

Heated intraperitoneal chemotherapy associated with longer survival in ovarian cancer

Phase II trial analysis shows higher ORR in HR MDS when treated with bexmarilimab + azacitidine

Researchers identify novel molecular target for pancreatic cancer

Inherited cancer mutations may drive tumor growth, study shows

Gene-based blood test for melanoma may detect early signs of cancer return

Researchers explore adapted Argentine tango dance therapy for cancer survivors at Ohio State

Drugs & Targets

FDA approves nivolumab + ipilimumab for unresectable or metastatic HCC

FDA to phase out animal testing requirement for monoclonal antibodies, other drugs

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