William Kaelin, Peter Ratcliffe, and Gregg Semenza receive 2016 Lasker Award for basic medical research

In The Headlines: Is early detection always good? Inside NCI’s MCD feasibility trial.

Do multi-cancer detection tests provide a net benefit? NCI aims to answer this question, beginning with the Vanguard feasibility trial which recently started accruing patients.

July 30, 2025

Vol.51 No.29

Clinical Conversation with The Cancer Letter

Will MCD tests revolutionize cancer screening? NCI begins enrollment in Vanguard “feasibility” trial to start finding out

The first large cancer screening/early detection initiative to be launched in 2025—the NCI-funded Vanguard study of multi-cancer detection tests—has started accruing patients through nine sites across the U.S.

July 25, 2025

Vol.51 No.29

By Sara Willa Ernst, Jacquelyn Cobb and Paul Goldberg

Conversation with The Cancer Letter

Robert Winn: If Medicaid gets massive cuts or goes away, where will these patients get care?

On July 4, President Donald Trump signed into law “The One Big Beautiful Bill Act,” which is expected to deal a massive blow to Medicaid coverage and leave millions without insurance by instituting a work requirement for beneficiaries.

July 25, 2025

Vol.51 No.29

By Sara Willa Ernst

Oncologist biotech entrepreneur George Tidmarsh joins FDA as CDER director
His appointment came out of “proximity” to Makary and Bhattacharya

In a move that will have direct impact on approval of cancer drugs, George Francis Tidmarsh, an oncologist and a longtime pharmaceutical executive, was named director of the FDA Center for Drug Evaluation and Research.

July 25, 2025

Vol.51 No.29

By Claire Marie Porter

City of Hope brings evidence-based approaches to integrative oncology

The landscape of cancer care is evolving rapidly, with growing recognition that optimal patient outcomes require a whole-person care approach that goes beyond cytotoxic and targeted therapies.

FY25 paylines drop to 4th percentile—a historic low—as NCI braces for Trump’s FY26 budget cuts

NCI announced that the paylines for R01 grants for established and new investigators are expected to drop to the 4th percentile—a historic low for the institute.

July 25, 2025

Vol.51 No.29

By Jacquelyn Cobb

William Kaelin, Peter Ratcliffe, and Gregg Semenza receive 2016 Lasker Award for basic medical research

YOU MAY BE INTERESTED IN

In The Headlines: Is early detection always good? Inside NCI’s MCD feasibility trial.

Will MCD tests revolutionize cancer screening? NCI begins enrollment in Vanguard “feasibility” trial to start finding out

Robert Winn: If Medicaid gets massive cuts or goes away, where will these patients get care?

Oncologist biotech entrepreneur George Tidmarsh joins FDA as CDER director
His appointment came out of “proximity” to Makary and Bhattacharya

City of Hope brings evidence-based approaches to integrative oncology

FY25 paylines drop to 4th percentile—a historic low—as NCI braces for Trump’s FY26 budget cuts

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William Kaelin, Peter Ratcliffe, and Gregg Semenza receive 2016 Lasker Award for basic medical research

YOU MAY BE INTERESTED IN

In The Headlines: Is early detection always good? Inside NCI’s MCD feasibility trial.

Will MCD tests revolutionize cancer screening? NCI begins enrollment in Vanguard “feasibility” trial to start finding out

Robert Winn: If Medicaid gets massive cuts or goes away, where will these patients get care?

Oncologist biotech entrepreneur George Tidmarsh joins FDA as CDER directorHis appointment came out of “proximity” to Makary and Bhattacharya

City of Hope brings evidence-based approaches to integrative oncology

FY25 paylines drop to 4th percentile—a historic low—as NCI braces for Trump’s FY26 budget cuts

Never miss an issue!

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Oncologist biotech entrepreneur George Tidmarsh joins FDA as CDER director
His appointment came out of “proximity” to Makary and Bhattacharya