James Downing named CEO of St. Jude

NCI’s new CCSG is the result of “thousands of hours” of listening, negotiations, surprises
New NOFO aims to shrink applications by 40%

Late next month, NCI is expected to publish the new criteria it uses to bestow designations on America’s network of cancer centers.

October 30, 2026

Vol.52 No.40

By Paul Goldberg

NCI

NCAB ad hoc working group seeks to define its role as it approves eight reissue concepts
“We could do a lot more than be another committee to check the RFAs before they go to the next level.”

Members of the National Cancer Advisory Board’s ad hoc Working Group on Extramural Research Concepts and Programs at a recent meeting struggled to define the new group’s the role and raised concerns about some initial growing pains.

MSK’s Andrea Cercek: Oncology faces learning curve as dostarlimab challenges dMMR rectal cancer standard of care

Earlier this week, FDA granted an accelerated approval to dostarlimab-gxly (Jemperli), for adults with previously untreated stage 2 or stage 3 rectal cancer that is mismatch repair deficient or microsatellite instability-high, marking a celebratory moment for the field.

October 30, 2026

Vol.52 No.40

By Jacquelyn Cobb

Cancer History Project

Facing stage 4 cholangiocarcinoma, Keaton Herzer moved mountains to take off-label therapy, get a transplant
Two years later, he has no evidence of disease

Keaton Herzer had never even heard of cholangiocarcinoma when he was diagnosed in 2025.

October 30, 2026

Vol.52 No.40

By Deborah Doroshow and Sara Willa Ernst

Lifesaving vaccines: Using KRAS to harness the power of the immune system

Neeha Zaidi, MD, is turning the tables on pancreatic cancer. Mutations to a gene called KRAS—a cancer driver common to almost all pancreatic cancers—are now a target for prevention and treatment.

October 30, 2026

Vol.52 No.40

By Valerie Mehl

Cancer Policy

HHS announces initiative to improve breast cancer screening and early detection

HHS, through the recently announced Office of Women’s Health, announced taht it will be pursuing a collaboration with the Agency for Healthcare Research and Quality and DenseBreast-info.org to strengthen breast cancer screening, expand breast density education, and improve timely diagnostic follow-up, particularly for midlife women.

October 30, 2026

Vol.52 No.40

By Claire Marie Porter

James Downing named CEO of St. Jude

YOU MAY BE INTERESTED IN

NCI’s new CCSG is the result of “thousands of hours” of listening, negotiations, surprises
New NOFO aims to shrink applications by 40%

NCAB ad hoc working group seeks to define its role as it approves eight reissue concepts
“We could do a lot more than be another committee to check the RFAs before they go to the next level.”

MSK’s Andrea Cercek: Oncology faces learning curve as dostarlimab challenges dMMR rectal cancer standard of care

Facing stage 4 cholangiocarcinoma, Keaton Herzer moved mountains to take off-label therapy, get a transplant
Two years later, he has no evidence of disease

Lifesaving vaccines: Using KRAS to harness the power of the immune system

HHS announces initiative to improve breast cancer screening and early detection

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James Downing named CEO of St. Jude

YOU MAY BE INTERESTED IN

NCI’s new CCSG is the result of “thousands of hours” of listening, negotiations, surprisesNew NOFO aims to shrink applications by 40%

NCAB ad hoc working group seeks to define its role as it approves eight reissue concepts“We could do a lot more than be another committee to check the RFAs before they go to the next level.”

MSK’s Andrea Cercek: Oncology faces learning curve as dostarlimab challenges dMMR rectal cancer standard of care

Facing stage 4 cholangiocarcinoma, Keaton Herzer moved mountains to take off-label therapy, get a transplantTwo years later, he has no evidence of disease

Lifesaving vaccines: Using KRAS to harness the power of the immune system

HHS announces initiative to improve breast cancer screening and early detection

Never miss an issue!

Login

NCI’s new CCSG is the result of “thousands of hours” of listening, negotiations, surprises
New NOFO aims to shrink applications by 40%

NCAB ad hoc working group seeks to define its role as it approves eight reissue concepts
“We could do a lot more than be another committee to check the RFAs before they go to the next level.”

Facing stage 4 cholangiocarcinoma, Keaton Herzer moved mountains to take off-label therapy, get a transplant
Two years later, he has no evidence of disease