The Cancer Letter

The leading source for information on the issues that shape oncology since 1973

Guest Editorial

Weill Cancer Hub East to investigate connections between metabolism and anti-tumor immunity

Weill Cornell, Rockefeller, Princeton and the Ludwig Institute for Cancer Research showcase the power of collaboration

Share on facebook
Share on twitter
Share on linkedin
Share on email
Share on print
BYLINE
IN THIS ISSUE
BYLINEDOWNLOAD PDFTABLE OF CONTENTS

The immune system can be a powerful tool to control cancer. Immune cells within our body detect cancer cells and release payloads that kill them. Transformative science in the last decade has led to the development of therapies that enhance the ability of our immune cells to carry out this function. These therapies, including checkpoint blockade and CAR-T cells, have been lifesaving for many patients that before had untreatable cancer. But, sadly, a majority of patients with advanced solid tumors still succumb to their disease. 

To access this subscriber-only content please log in or subscribe.

If your institution has a site license, log in with IP-login or register for a sponsored account.*
*Not all site licenses are enrolled in sponsored accounts.

Login Subscribe
Byline
Jedd D. Wolchok, MD, PhD
Meyer Director, Sandra and Edward Meyer Cancer Center, Professor of medicine, New York-Presbyterian/Weill Cornell Medical Center
Joshua D. Rabinowitz, MD, PhD
Professor of chemistry and genomics, Director, Ludwig Princeton Branch, Princeton University
Sohail Tavazoie, MD, PhD
Leon Hess Professor, Senior Attending Physician, The Rockefeller University
Table of Contents

YOU MAY BE INTERESTED IN

Clinical Roundup

Investigational Orca-T treatment for hematologic malignancies meets primary endpoint in phase III trial

Orca Bio, a late-stage biotechnology company, on March 17 announced results from the pivotal phase III Precision-T study of Orca-T, its lead investigational allogeneic T-cell immunotherapy, in patients with acute myeloid leukemia, acute lymphoblastic leukemia, high-risk myelodysplastic syndrome and mixed-phenotype acute leukemia. Orca-T is manufactured using highly purified regulatory T-cells, hematopoietic stem cells and conventional T-cells derived from peripheral blood from either related or unrelated matched donors.
Clinical Roundup

Chemo-immunotherapy approach shows potential benefit in advanced HPV-negative head-and-neck cancer

Researchers from the University of Chicago Medicine Comprehensive Cancer Center demonstrated the potential of a novel treatment approach including immunotherapy to treat advanced human papillomavirus-negative head-and-neck squamous cell carcinoma. More than half of study participants had 50% or more of their tumors shrink after receiving the immunotherapy drug nivolumab with chemotherapy, followed by response-adaptive chemo-radiation therapy. 
Byline
Jedd D. Wolchok, MD, PhD
Meyer Director, Sandra and Edward Meyer Cancer Center, Professor of medicine, New York-Presbyterian/Weill Cornell Medical Center
Joshua D. Rabinowitz, MD, PhD
Professor of chemistry and genomics, Director, Ludwig Princeton Branch, Princeton University
Sohail Tavazoie, MD, PhD
Leon Hess Professor, Senior Attending Physician, The Rockefeller University
Table of Contents

Never miss an issue!

Get alerts for our award-winning coverage in your inbox.

Login

Site license subscribers:
Log in with your IP | Register a sponsored account