Mayo Clinic performs world’s first known successful total larynx transplant in a patient with active cancer

Filippo Milano named inaugural Endowed Chair in Cord Blood Research at Fred Hutch

Filippo Milano, a hematologist-oncologist and clinical researcher, was named the inaugural Endowed Chair in Cord Blood Research at Fred Hutchinson Cancer Center.

April 11, 2025

Vol.51 No.14

Clinical Roundup

KRAS mutation is a significant predictor of metastasis and survival in pancreatic cancer, study shows

A new study by Mayo Clinic Comprehensive Cancer Center researchers found that the presence of a specific genetic mutation—KRAS circulating tumor DNA—strongly indicates a higher risk of cancer spread and worse survival rates for patients with pancreatic ductal adenocarcinoma.

March 21, 2025

Vol.51 No.11

Clinical Roundup

Chemo-immunotherapy approach shows potential benefit in advanced HPV-negative head-and-neck cancer

Researchers from the University of Chicago Medicine Comprehensive Cancer Center demonstrated the potential of a novel treatment approach including immunotherapy to treat advanced human papillomavirus-negative head-and-neck squamous cell carcinoma. More than half of study participants had 50% or more of their tumors shrink after receiving the immunotherapy drug nivolumab with chemotherapy, followed by response-adaptive chemo-radiation therapy.

March 14, 2025

Vol.51 No.10

Clinical Roundup

Self-driving microscope solves previous challenges in microscopy

UT Southwestern Medical Center researchers developed a “self-driving” microscope that solves two challenges that have long plagued microscopy: 1) imaging living cells or organisms at dramatically different scales, and 2) following a specific structure or area of interest over long periods of time.

March 14, 2025

Vol.51 No.10

Clinical Roundup

First FDA-approved robot-assisted microsurgery for head-and-neck cancer performed at Cedars-Sinai

Cedars-Sinai performed the first robot-assisted microsurgical head-and-neck cancer reconstructive surgery in the United States after the robot device received FDA approval for the procedure.

February 21, 2025

Vol.51 No.07

Clinical Roundup

Mayo Clinic researchers identify new immunotherapy target for ovarian cancer

Mayo Clinic researchers have discovered a new immunotherapy target, a cryptic antigen, may be key in helping the immune system fight tumors in ovarian cancer. The study, published in Science Advances, could improve treatment approaches for this type of cancer.

February 21, 2025

Vol.51 No.07

Mayo Clinic performs world’s first known successful total larynx transplant in a patient with active cancer

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Filippo Milano named inaugural Endowed Chair in Cord Blood Research at Fred Hutch

KRAS mutation is a significant predictor of metastasis and survival in pancreatic cancer, study shows

Chemo-immunotherapy approach shows potential benefit in advanced HPV-negative head-and-neck cancer

Self-driving microscope solves previous challenges in microscopy

First FDA-approved robot-assisted microsurgery for head-and-neck cancer performed at Cedars-Sinai

Mayo Clinic researchers identify new immunotherapy target for ovarian cancer

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