Trial shows atezolizumab combined with carboplatin has efficacy in TNBC

SITC seeks applications for two fellowships

Applications are now being accepted for the Society for Immunotherapy of Cancer fellowship opportunities. This year, SITC is offering two fellowships totaling $150,000 in funding.

March 20, 2026

Vol.52 No.11

Clinical Roundup

Atirmociclib combination produces positive topline results in phase II trial in second-line MBC indication

Positive topline results have come out of the randomized phase II FOURLIGHT-1 study evaluating atirmociclib in combination with fulvestrant, versus fulvestrant or everolimus plus exemestane, in people with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced or metastatic breast cancer who had received prior cyclin-dependent kinase 4/6 inhibitor-based treatment.

March 20, 2026

Vol.52 No.11

Guest Editorial

As more people are surviving cancer, we must continue funding bold science

The cancer research community has a reason to celebrate. For the first time, 70% of people are living at least five years beyond their cancer diagnosis. And, as importantly, cancer death rates have been dropping relentlessly—by more than a third since 1991.

Phase III persevERA study of giredestrant combination in ER-positive advanced breast cancer does not meet primary objective

The phase III persevERA Breast Cancer study, evaluating investigational giredestrant in combination with palbociclib for people with oestrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer, did not meet its primary objective of a statistically significant improvement in progression-free survival in the intent-to-treat population versus letrozole plus palbociclib, but a numerical improvement was observed.

March 13, 2026

Vol.52 No.10

Cancer Policy

Mt. Sinai forms committee to probe Epstein links to breast center founder Eva Dubin, other faculty members

Mount Sinai hospital has formed a committee to investigate the ties between Jeffrey Epstein and Eva Dubin a Swedish physician and philanthropist who founded the Dubin Breast Center at the Tisch Cancer Institute whose name is featured prominently in the Epstein files.

March 06, 2026

Vol.52 No.09

By Claire Marie Porter and Sara Willa Ernst

Clinical Roundup

TNBC can become resistant to therapy in more than one way, Baylor study finds

About 50% of triple-negative breast cancer patients develop resistance to therapy. When resistance arises, tumors are more likely to come back after the original treatment, significantly reducing the chances of survival.

March 06, 2026

Vol.52 No.09

Trial shows atezolizumab combined with carboplatin has efficacy in TNBC

YOU MAY BE INTERESTED IN

SITC seeks applications for two fellowships

Atirmociclib combination produces positive topline results in phase II trial in second-line MBC indication

As more people are surviving cancer, we must continue funding bold science

Phase III persevERA study of giredestrant combination in ER-positive advanced breast cancer does not meet primary objective

Mt. Sinai forms committee to probe Epstein links to breast center founder Eva Dubin, other faculty members

TNBC can become resistant to therapy in more than one way, Baylor study finds

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