SOLO-1 phase III trial demonstrates Lynparza maintenance therapy cut the risk of disease progression or death by 70% in advanced BRCA-mutated ovarian cancer

Under the lens: Taking a close look at the NIH and FDA declarations on animal-based research

In April 2025, announcements from the two most influential biomedical agencies in the US, the FDA and the NIH, declared that both will seek to reduce and minimize animal-based testing and experimentation. These declarations sparked joy in some circles, and deep concern in others that was reflected in a 28% fall in the share price of Charles River Labs (NYSE: NYSE:CRL).

October 17, 2025

Vol.51 No.38

By Edison T. Liu

News Analysis Regulatory News

How animal testing became a MAHA political wedge issue
While cancer scientists say NIH, FDA moves are premature, animal rights advocates say changes aren’t drastic enough

Bowing to the growing animal rights movement, FDA and NIH have made policy changes to discourage animal testing, instead favoring alternative research models.

October 17, 2025

Vol.51 No.38

By Claire Marie Porter and Jacquelyn Cobb

Guest Editorial

Study finds no correlation between cancer burden in catchment areas and cancer centers’ CCSG funding

When the idea of looking at cancer center funding and the cancer burden of cancer center catchment areas came to us in the summer of 2024, we lived in a different context.

October 17, 2025

Vol.51 No.38

By Todd Burus, Caree McAfee and Pamela C. Hull

Why both somatic and germline genomic profiling are essential for precision oncology

Over the past three decades, cancer genetics has transformed precision oncology. Germline testing has advanced from single-gene Sanger sequencing to parallel sequencing of hundreds of genes, while tumor (somatic) testing has expanded with the rise of targeted therapies based on point mutations, copy number changes and other alterations.

October 17, 2025

Vol.51 No.38

By Heather Hampel and David W. Craig

Cancer Policy

Dems push GOP to extend ACA credits as part of a deal to end the government shutdown

Millions of Americans with Affordable Care Act marketplace health insurance will face higher costs next year if Congress doesn’t extend enhanced premium tax credits that have made the plans more affordable for low- and middle-income enrollees.

October 17, 2025

Vol.51 No.38

By Claire Marie Porter

Cancer Policy

Federal judge puts temporary block on new round of CDC and HHS layoffs

A federal judge issued a temporary restraining order on Oct. 15, ordering the Trump administration to reverse the wave of layoffs that the administration is using as a pressure tactic intended to force the Democrats to accept cuts to popular health programs and reopen the government.

October 17, 2025

Vol.51 No.38

By Sara Willa Ernst

SOLO-1 phase III trial demonstrates Lynparza maintenance therapy cut the risk of disease progression or death by 70% in advanced BRCA-mutated ovarian cancer

YOU MAY BE INTERESTED IN

Under the lens: Taking a close look at the NIH and FDA declarations on animal-based research

How animal testing became a MAHA political wedge issue
While cancer scientists say NIH, FDA moves are premature, animal rights advocates say changes aren’t drastic enough

Study finds no correlation between cancer burden in catchment areas and cancer centers’ CCSG funding

Why both somatic and germline genomic profiling are essential for precision oncology

Dems push GOP to extend ACA credits as part of a deal to end the government shutdown

Federal judge puts temporary block on new round of CDC and HHS layoffs

Renew today!

Subscriber content

Never miss an issue!

Login

SOLO-1 phase III trial demonstrates Lynparza maintenance therapy cut the risk of disease progression or death by 70% in advanced BRCA-mutated ovarian cancer

YOU MAY BE INTERESTED IN

Under the lens: Taking a close look at the NIH and FDA declarations on animal-based research

How animal testing became a MAHA political wedge issueWhile cancer scientists say NIH, FDA moves are premature, animal rights advocates say changes aren’t drastic enough

Study finds no correlation between cancer burden in catchment areas and cancer centers’ CCSG funding

Why both somatic and germline genomic profiling are essential for precision oncology

Dems push GOP to extend ACA credits as part of a deal to end the government shutdown

Federal judge puts temporary block on new round of CDC and HHS layoffs

Never miss an issue!

Login

How animal testing became a MAHA political wedge issue
While cancer scientists say NIH, FDA moves are premature, animal rights advocates say changes aren’t drastic enough