In follow-up data from the phase III ALEX study, an initial treatment Alecensa (alectinib) significantly reduced the risk of disease progression or death by 57 percent (hazard ratio= 0.43, 95 percent CI: 0.32-0.58) compared to crizotinib after two years of follow-up in people with anaplastic lymphoma kinase-positive metastatic non-small cell lung cancer, as assessed by the investigator.
New research led by Friends of Cancer Research demonstrates that decreases in circulating tumor DNA after initiation of treatment are associated with improved overall survival in patients with advanced non-small cell lung cancer treated with immunotherapy or chemotherapy.
