Two studies presented at the 2014 Multidisciplinary Head and Neck Cancer Symposium suggested that positive HPV status could be used as a biomarker indicator related to improved survival.
A summary of a large study concluded that women with BRCA1 genetic mutations should undergo preventive ovarian surgery by age 35 to achieve the greatest reduction in their risks of breast and ovarian cancer.
A phase III study of Avastin failed to increase overall survival or statistically significant progression-free survival for glioblastoma patients in the frontline setting. The international study was a collaboration among the cooperative groups RTOG, NCCTG, and ECOG.
FDA granted accelerated approval for Mekinist (trametinib) in combination with Tafinlar (dabrafenib) for unresectable melanoma or metastatic melanoma with BRAF V600E or V600K mutations.
The National Cancer Institute Cancer Therapy Evaluation Program approved the following clinical research studies last month. For further information, contact the principal investigator listed.
Clinical validation study results of a microRNA signature classifier lung cancer assay demonstrated that a blood-based test can significantly reduce the high false-positive rate associated high-resolution imaging, specifically with low-dose computed tomography.
A series of studies of the Oncotype DX colon cancer test were presented at the 2014 American Society of Clinical Oncology Gastrointestinal Cancer Symposium.
A study in aggressive prostate cancer confirmed that epigenetic profiling of selected genes can provide prognostic information corresponding to Gleason score.
A post-hoc analysis of results from the phase III HEAT Study of ThermoDox, a heat-activated liposomal encapsulation of doxorubicin in combination with radio frequency ablation, suggests the agent may significantly improve overall survival in primary liver cancer patients that receive RFA treatment for 45 minutes or more.
Patients with advanced kidney cancer lived an average of seven months longer if they were taking a common type of high blood pressure medication during treatment, according to an analysis of clinical trials data.
