publication date: Sep. 11, 2020
Issue 34 - Sep. 11, 2020
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  • NCI will form an ad hoc committee to review screening trials

    The future of ECOG-ACRIN’s slowly-accruing TMIST is in question

    NCI’s cancer screening trials may be falling victim to the COVID-19 pandemic.

    Last week, the institute asked the National Cancer Advisory Board to form an ad hoc group that would provide guidance on screening trials, starting with the Tomosynthesis Mammographic Imaging Screening Trial, TMIST for short (The Cancer LetterSept. 4, 2020).

  • Conversation with The Cancer Letter

    Mitch Schnall: “We don’t want to lose momentum as this review is happening”

    NCI’s publicly announced move to create an ad hoc working group that would review the feasibility and viability of the TMIST trial threatens to undercut this trial, said Mitchell Schnall, co-chair of ECOG-ACRIN Cancer Research Group, the group conducting the study.

  • Guest Editorial

    Toward individualized breast cancer screening strategies—TMIST

    Breast cancer screening is beset with controversy, despite strong evidence from multiple randomized trials that screening mammography, in conjunction with modern therapies, reduces breast cancer mortality and treatment morbidity.

  • A reminder: The real goal is saving lives

    Dear Editor,

    was disappointed to see that you reported on the results of the IMpassion 131 trial, without context. [The Cancer LetterSept. 4, 2020]

  • Guest Editorial

    An open letter to Sen. Kamala Harris

    Honorable Sen. Harris and colleagues,

    write this letter to you as an advocate for women with malignant uterine soft tissue tumors—and to commend you on the introduction of The Uterine Fibroids Research and Education Act in the United States Congress.

  • In Brief

    • Mays Cancer Center receives renewal of NCI designation
    • Justin Leung receives $1.9 million in funds to research DNA damage response
    • Surupa Sen Gupta joins Maryland Oncology Hematology
  • TCCL Logo

  • Clinical Roundup

    • JNCCN study sheds light on multi-organ adverse events from immunotherapy
    • City of Hope scientists combine oncolytic virus and CAR T in solid tumors
    • Phase II study of Tabrecta shows positive ORR for NSCLC
  • Drugs & Targets

    • Pralsetinib receives FDA approval for lung cancer with RET gene fusions
    • Oncomine Dx Target Test receives FDA approval as first NGS-based companion diagnostic for RET fusion + NSCLC
    • FDA issues alert about efficacy and potential safety concerns with atezolizumab in combination with paclitaxel for treatment of breast cancer
    • Oncocyte receives final pricing decision for DetermaRx Molecular Test for lung cancer from CMS
    • MD Anderson, Xencor collaborate on investigational XmAb drug candidates

Copyright (c) 2020 The Cancer Letter Inc.