Epidermal growth factor receptor signaling in the tissue around oral cancers both increases nerve sensitivity and makes opioids less effective, according to a study conducted by researchers at NYU, MD Anderson, and Loma Linda University. The finding points to a shared mechanism underlying both oral cancer pain and opioid tolerance, and a possible new treatment strategy for both.
Researchers at the School of Dentistry at UT Health San Antonio, the academic health center of the University of Texas at San Antonio, have been awarded three multi-year grants totaling $6 million from NIH to address treatment and pain management for oral cancer.
