Mayo Clinic researchers identify personalized approach to brain cancer monitoring

FDA grants Breakthrough Therapy designation for B7-H3 CAR T-cell therapy for diffuse intrinsic pontine glioma

BrainChild Bio Inc. announced that its investigational B7-H3 targeting autologous CAR T-cell therapy has been granted Breakthrough Therapy designation by FDA for the treatment of diffuse intrinsic pontine glioma, an incurable pediatric brain tumor.

April 25, 2025

Vol.51 No.16

In Brief

Michael Chan named chair of Wake Forest’s Department of Radiation Oncology

Michael Chan was appointed chair of Wake Forest University’s Department of Radiation Oncology, which he has led as interim chair since 2023. In his permanent role, he will advance the clinical, research and education missions of the department, while optimizing care delivery and clinical operations.

March 28, 2025

Vol.51 No.12

Clinical Roundup

UT Health San Antonio-led research discovers how to slow or block recurrence of glioblastoma

Researchers at the University of Texas Health Science Center at San Antonio have discovered a way to delay or even block recurrence of the deadliest brain cancer after radiation.

March 28, 2025

Vol.51 No.12

Clinical Roundup

KRAS mutation is a significant predictor of metastasis and survival in pancreatic cancer, study shows

A new study by Mayo Clinic Comprehensive Cancer Center researchers found that the presence of a specific genetic mutation—KRAS circulating tumor DNA—strongly indicates a higher risk of cancer spread and worse survival rates for patients with pancreatic ductal adenocarcinoma.

March 21, 2025

Vol.51 No.11

Clinical Roundup

Classifying childhood brain cancers by immune response may improve diagnostics and treatments

Researchers and pediatric neurosurgeons at the University of Pittsburgh School of Medicine and UPMC Children’s Hospital of Pittsburgh developed a new way to profile brain cancers in children.

March 21, 2025

Vol.51 No.11

Clinical Roundup

Self-driving microscope solves previous challenges in microscopy

UT Southwestern Medical Center researchers developed a “self-driving” microscope that solves two challenges that have long plagued microscopy: 1) imaging living cells or organisms at dramatically different scales, and 2) following a specific structure or area of interest over long periods of time.

March 14, 2025

Vol.51 No.10

Mayo Clinic researchers identify personalized approach to brain cancer monitoring

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FDA grants Breakthrough Therapy designation for B7-H3 CAR T-cell therapy for diffuse intrinsic pontine glioma

Michael Chan named chair of Wake Forest’s Department of Radiation Oncology

UT Health San Antonio-led research discovers how to slow or block recurrence of glioblastoma

KRAS mutation is a significant predictor of metastasis and survival in pancreatic cancer, study shows

Classifying childhood brain cancers by immune response may improve diagnostics and treatments

Self-driving microscope solves previous challenges in microscopy

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