The Cancer Letter

Inside information on cancer research and drug development

Respect the role (and confidentiality) of the EAB at UCSD—and at all NCI-designated cancer centers

In Brief

Christina Annunziata named SVP for extramural discovery science at ACS
ACS, Color Health partner to increase access, adherence to cancer screening and prevention for U.S. employers, unions
Xavier Avat named chief business officer of Moffitt
Fox Chase’s Elizabeth Plimack appointed ASCO treasurer
Bonnie J. Addario receives 2023 Award for Leadership in Personalized Medicine
Ohio State opens outpatient cancer center

Drugs & Targets

FDA accepts sBLA for Keytruda in combination with chemotherapy in liver cancer indication
FDA approves BMS cell-manufacturing facility in Massachusetts
FDA approves Lynparza with abiraterone, prednisone (or prednisolone) for BRCA-mutated metastatic castration-resistant prostate cancer
FDA approves Posluma—first radiohybrid PSMA-targeted PET imaging agent for prostate cancer
FDA grants priority review to repotrectinib for locally advanced or metastatic ROS1-positive NSCLC
EMA CHMP recommends approval of Opdivo + chemo for the neoadjuvant treatment of PD-L1 positive, resectable NSCLC at a high risk of recurrence

In The Clinic

ComboMATCH trial—a collaboration across NCI and NCTN groups—matches patients with combination therapy trials based on tumor biology

ComboMATCH trial—a collaboration across NCI and NCTN groups—matches patients with combination therapy trials based on tumor biology
Cisplatin, carboplatin shortage prompts rationing of lifesaving drugs—patients will die
Continuous temperature tracking helps manage infection risk after CAR T-cell therapy
Trials & Tribulations
San Antonio Breast Cancer Symposium 2022 tackled big obstacles, recommended solutions for breast cancer progress
Trials & Tribulations
Pragmatica-Lung, a landmark pragmatic trial with registrational intent, starts enrollment

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The Cancer Letter is an independent weekly news publication and the leading source for information on the issues that shape oncology.

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