publication date: Feb. 28, 2017

Breast Cancer Blood Test That Detects Changes in Tumor DNA Predicts Survival in Advanced Disease

Results of a multicenter study of 129 women with advanced breast cancer show that a blood test that spots cancer-linked DNA correctly predicted that most of those patients with higher levels of the tumor markers died significantly earlier than those with lower levels.

The Johns Hopkins Kimmel Cancer Center scientists, who developed the test and led the study, say the results, if confirmed in more studies, suggest that the DNA detector, called cMethDNA, could be widely used to identify breast cancers at higher risk for recurrence and track the success or failure of treatment. Results of the study were published online Nov. 21 in the Journal of Clinical Oncology.

“There’s a great need in cancer patients to be able to quickly and easily assess if a particular treatment is working in order to switch to another if it’s not, thus avoiding wasted time, potential side effects and cost,” said Kala Visvanathan, professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health, professor of oncology at the Johns Hopkins University School of Medicine and director of the Clinical Cancer Genetics Program at the Johns Hopkins Kimmel Cancer Center. “Our study results, although preliminary, suggest that cMethDNA has the potential to be an effective way to do this for … Continue reading CCL Feb 2017 – Blood Test That Detects Changes in Tumor DNA Predicts Survival in Advanced Disease

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