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The Cancer Letter
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Epic EHR data: Cancer screenings nosedive in 2021 despite easing of COVID restrictions
Real-world Evidence

Epic EHR data: Cancer screenings nosedive in 2021 despite easing of COVID restrictions

Routine screening procedures for breast, colon, and cervical cancers in the first half of 2021 have failed to recover, falling by about a third below historical baselines, even as Americans are resuming normal activities.
September 17, 2021
Vol.47 No.34
By Matthew Bin Han Ong
COTA’s Miruna Sasu: I left pharma to “turn the spigot on” in the real-world data industry
Conversation with The Cancer Letter

COTA’s Miruna Sasu: I left pharma to “turn the spigot on” in the real-world data industry

Miruna Sasu spent more than 20 years as a digital health and innovation expert at life sciences companies—then came a realization
June 11, 2021
Vol.47 No.23
By Matthew Bin Han Ong
Precision oncology must evolve to address health disparities
FreeTrials & Tribulations

Precision oncology must evolve to address health disparities

Every person facing a cancer diagnosis deserves access to the best possible tests and treatments for their disease. It’s really that simple. Even better—it’s entirely feasible. 
June 04, 2021
Vol.47 No.22
By Brandon Mahal and Jeffrey Venstrom
Study of NSCLC, melanoma outcomes points to surrogacy between real-world endpoints and clinical trial endpoints
Real-world Evidence

Study of NSCLC, melanoma outcomes points to surrogacy between real-world endpoints and clinical trial endpoints

A collaboration of 10 healthcare research organizations has demonstrated that real-world endpoints can be used to describe patient outcomes that are analogous to results generated through conventional endpoints in clinical trials.
September 25, 2020
Vol.46 No.36
By Matthew Bin Han Ong
Prostate cancer patients aren’t getting testosterone suppression injections on time

Prostate cancer patients aren’t getting testosterone suppression injections on time
Payment policies blamed for non-compliance with treatment guidelines

The vast majority of patients with prostate cancer in the United States don't receive androgen deprivation therapy injections on time. Up to 84% of injections are delayed for patients on a 28-day schedule, according to an authoritative study published in the The Journal of Urology.
July 24, 2020
Vol.46 No.30
By Matthew Bin Han Ong
COVID-19 vs. community oncology: Flatiron’s data provides first damage assessment
COVID-19 & CancerFree

COVID-19 vs. community oncology: Flatiron’s data provides first damage assessment

Community oncology practices in the United States are reeling from a sharp decrease in business—whether you look at new patients, chemotherapy visits, or non-chemo visits—the result of reduced activity and stay-at-home orders across the country to mitigate the spread of SARS-CoV-2.
May 01, 2020
Vol.46 No.18
By Matthew Bin Han Ong
Real-world evidence at a glance: How a collaboration of “frenemies” produced common definitions for real-world endpoints
FreeReal-world Evidence

Real-world evidence at a glance: How a collaboration of “frenemies” produced common definitions for real-world endpoints

Ten health care research organizations, with help from FDA and NCI, have developed a set of common definitions for real-world endpoints, including overall survival, progression-free survival, and other non-traditional endpoints.
November 22, 2019
Vol.45 No.44
By Matthew Bin Han Ong
Real-world data, evidence should be leveraged in clinical research to better include and ultimately treat larger patient populations
Free

Real-world data, evidence should be leveraged in clinical research to better include and ultimately treat larger patient populations

The growth of personalized medicine in oncology continues to fuel a shift from traditional chemotherapies to immunotherapy. Currently, there are more than 30 immunotherapies approved for use in the United States, with more than 2,300 immunotherapy clinical trials listed on ClinicalTrials.gov.
October 18, 2019
Vol.45 No.39
By Sarah Alwardt
Oncologists quickly react to label changes for immunotherapies, a study by Penn, Flatiron shows
Free

Oncologists quickly react to label changes for immunotherapies, a study by Penn, Flatiron shows

In an unprecedented use of real-world data, researchers at the University of Pennsylvania and Flatiron Health have determined that oncologists are responding quickly to label restrictions announced by FDA.
September 27, 2019
Vol.45 No.36
By Matthew Bin Han Ong
Challenges to leveraging real-world evidence for FDA approval

Challenges to leveraging real-world evidence for FDA approval

The number of approved cancer therapies continues to rise, with 63 cancer drugs launched within the past five years.
September 20, 2019
Vol.45 No.35
By Ash Malik

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