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Clinical Roundup

Keytruda meets primary endpoint of OS in HER2-negative gastric cancer

Topline results from the pivotal phase III KEYNOTE-859 trial investigating Keytruda (pembrolizumab), in combination with chemotherapy for the first-line treatment of patients with human epidermal growth factor receptor 2 (HER2)-negative locally advanced unresectable or metastatic gastric or GEJ adenocarcinoma, were positive. 
December 02, 2022
Vol.48 No.43
In Brief

John Wayne Cancer Foundation funds research to prevent stomach cancer in Navajo Nation

In celebration of November’s Native American Heritage Month and Stomach Cancer Awareness Month observances, the John Wayne Cancer Foundation is funding research that will allow doctors to assess barriers to treatment of H. pylori and disseminate findings to community health partners to reduce the occurrence of stomach cancer. 
November 18, 2022
Vol.48 No.42
Drugs & Targets

Organon launches Herceptin biosimilar in Canada

Organon launched the distribution of Ontruzant, a biosimilar of Herceptin, in Canada, providing an additional treatment option for Canadian adults diagnosed with early breast cancer, metastatic breast cancer, and metastatic gastric cancer.
November 18, 2022
Vol.48 No.42

Differences in subtypes may determine prognosis and response to treatment

Molecular classification of the four distinct subtypes of gastric cancer could potentially shape tailored treatment options by helping to predict survival outcomes and patients' response to chemotherapy.
August 03, 2017
Vol.40 No.07

Opdivo Demonstrated Improved Survival in Advanced Gastric Cancer in Phase III Study

Bristol-Myers Squibb Company announced the results of ONO-4538-12 demonstrating Opdivo (nivolumab) significantly reduced the risk of death by 37% (HR 0.63; p<0.0001) in patients with previously treated advanced gastric cancer refractory to or intolerant of standard therapy, a condition without current standard-of-care treatments.
February 28, 2017
Vol.40 No.02
FreeTCCL Archive

Phase III Cyramza Trial Meets OS Primary Endpoint

A global phase III trial of Cyramza (ramucirumab) in combination with paclitaxel in patients with advanced gastric cancer or gastroesophageal junction adenocarcinoma met its primary endpoint of median overall survival.
October 01, 2014
Vol.37 No.09

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