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Clinical Roundup

Long-term data from AstraZeneca/Merck’s Lynparza shows survival benefit in ovarian cancer

Lynparza (olaparib) showed clinically meaningful survival benefit as first line therapy in certain patients with ovarian cancer, according to long-term data.
September 16, 2022
Vol.48 No.33
Clinical Roundup

ADAURA trial shows positive results in early-stage NSCLC

Newly released results from the phase III ADAURA trial reveal that osimertinib yielded a 5.5-year median disease-free survival in the post-surgical treatment of patients with EGFR-mutated lung cancer, and nearly three in four patients treated with adjuvant osimertinib were disease-free at four years. 
September 16, 2022
Vol.48 No.33
Drugs & Targets

FDA approves first targeted therapy for HER2-low breast cancer

FDA approved Enhertu (fam-trastuzumab-deruxtecan-nxki) for unresectable or metastatic HER2-low breast cancer. 
September 09, 2022
Vol.48 No.32
Drugs & Targets

FDA grants accelerated approval to Enhertu for HER2-mutant NSCLC and companion diagnostic

FDA granted accelerated approval to Enhertu (fam-trastuzumab deruxtecan-nxki) for adult patients with unresectable or metastatic NSCLC whose tumors have activating HER2 mutations, as detected by an FDA-approved test, and who have received a prior systemic therapy. 
September 09, 2022
Vol.48 No.32
Drugs & Targets

FDA approves Imfinzi for locally advanced or metastatic biliary tract cancer

FDA has approved Imfinzi (durvalumab), in combination with gemcitabine and cisplatin for adult patients with locally advanced or metastatic biliary tract cancer.
September 09, 2022
Vol.48 No.32
Drugs & Targets

AstraZeneca to acquire TeneoTwo and its clinical-stage T-cell engager, TNB-486

AstraZeneca will acquire TeneoTwo Inc., including its phase I clinical-stage CD19/CD3 T-cell engager, TNB-486, currently under evaluation in relapsed and refractory B-cell non-Hodgkin lymphoma.
July 08, 2022
Vol.48 No.27
Funding Opportunities

AstraZeneca opens call for proposals for R&D Postdoctoral Challenge

AstraZeneca has launched the global R&D Postdoctoral Challenge to help accelerate the treatment of complex diseases, including cancer.
March 25, 2022
Vol.48 No.12

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