Duke Scandal
Duke University Suspends Two Clinical Trials After Journal Paper Questions Assay Validity
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Moffitt Ends Pilot Study Based On Duke Test, Says Action Unrelated
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Duke Halts Third Trial; Coauthor Disputes Claim That Data Validation Was Blinded
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Duke Plans To Restart Three Trials Using Tumor Microarray Analysis
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Report Doesn’t Quell Concerns About Duke Genomics Research, Biostatisticians Say
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The Cancer Letter Obtains “Confidential” Documents From Duke IRB Investigation
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NCI Raises New Questions About Duke Genomics Research, Cuts Assay From Trial
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A high-profile cancer genomics researcher at Duke University claimed in multiple grant applications that he had been a Rhodes scholar, when, in fact, the Rhodes Trust states flatly that he was not.
The Lancet Oncology Issues “Expression Of Concern” Over Paper
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By Defending Potti, Duke Officials Become Target Of Charges Of Institutional Failure
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Duke Vice Dean Cuffe Promises Complete, Independent Probe Of Work By Potti, Nevins.
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Potti Claimed Rhodes Credential in Bio Submitted for DOD Funding
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Michigan Scientist David Beer Sought Retraction Of Potti’s NEJM Paper Over Misuse Of His Data
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Varmus, Duke Ask IOM To Investigate Potti’s Scientific Work, Clinical Trials
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IOM To Form Committee To Investigate Duke Genomics Research
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An Impromptu Group Proposes Standards For Publication Of Genomics Research
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IOM Review Of Duke Genomics Trials To Focus On Validation, Scientific Criteria
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Retraction Based On Data Given To Duke Last November, But Apparently Disregarded
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Nevins Retracts Key Paper By Duke Group, Raising Question Of Harm To Patients
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Duke Retraction May Alter IOM Investigation; Review Panel Membership Announced
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JCO Retracts Key Duke Genomics Paper; Duke Shuts Down Three Phase II Trials
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NCI Releases 550 Pages of Internal Documents Related To Duke Scandal
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IOM Committee Will Probe Duke Scandal Together With Other “Omics” Case Studies
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Duke Deans Acknowledge Withholding Key Document From Outside Reviewers
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FDA Auditors Spend Two Weeks At Duke, Nevins Loses Position in Reorganization
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Nevins: Duke Administration Did a “Very Good Job” Of Handling The Crisis
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Guest Editorial: Anil Potti Hires “Online Reputation Managers” As Journals Retract His Biomarker Research
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A Year at NCI: Harold Varmus Reflects On Provocative Questions, The Duke Scandal, Financial Disaster And Grant Review
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Clinical Trial Participants Sue Duke University, Potti, Nevins and Others for Causing Harm
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Duke Researchers Retract Paper from Blood; Dozens of Retractions of Potti’s Work Expected
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Excerpts From Potti’s Application to Practice Medicine In South Carolina
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Duke University Settles 11 Medical Malpractice Cases Related to Potti’s trials
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Anil Potti Reprimanded by North Carolina Licensure Board
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Anil Potti Explains: “Coming from India, I Did Not Know This Was Not The Real Rhodes Scholarship”
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News Analysis by Keith Baggerly: Duke Trials Went On Despite FDA Statements
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FDA Didn’t Punish Duke for Failing To Seek Proper Regulatory Clearance for Three Trials
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Nevins Reverses Position, Claims Potti Manipulated Data For Basis of Clinical Trials
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IOM Omics Committee Offers Blueprint to Prevent Other Duke-Style Disasters
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Exit Joseph Nevins: Duke’s Genomics Luminary Quietly Leaves
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Duke University would have avoided embarrassment, a misconduct investigation and a lawsuit, had its top administrators paid closer attention to a thoughtful report by a medical student who saw problems in the lab of the disgraced scientist Anil Potti.
Repeating the Third Year?
Nevins Acknowledges Gravity of the Situation
New Perspective on Nevins and Potti
In May 2008, the Blue Devils of genomic medicine were facing a mortal threat.
On Jan. 9, 2015, The Cancer Letter reported that Duke University received information in early 2008 that called into question the validity of the methodology and results published by the Anil Potti research group. Potti, along with his mentor and co-author Joseph Nevins, had galvanized the world of cancer research in 2006 and 2007 with their reports of successful gene expression tests for directing cancer therapy, the “holy grail” of cancer research. The 2008 information came in the form of a letter from a third-year medical student, Brad Perez, who was working in Potti's lab. The letter, which does not seem to have been given any credence at the time, described with precision the problems that eventually resulted in the termination of clinical trials and the subsequent retractions, beginning in 2011, of at least ten (and counting) papers from major scientific journals.