Vol.

No.

September 13, 2019Sep 13, 2019

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Cover Story

Why CAR-T policymaking is broken, and why we need to fix it

By Michael Kolodziej, Louis Jacques and Marc Samuels

The initial reports of the near-miraculous benefits of CAR-T in pediatric acute lymphoblastic leukemia generated tremendous excitement—there was a Lazarus-like quality to these stories.

The 2019 Lasker Awards go to: Max D. Cooper, Jacques Miller, Michael Shepard, Dennis J. Slamon, Axel Ullrich, and Gavi, the Vaccine Alliance

Clinical Conversation with The Cancer Letter Free

Michigan's Philip Stella receives NCORP 2019 Harry Hynes Award

By Paul Goldberg

In Brief

DeAngelis named MSK physician-in-chief, chief medical officer

Bondy named chair of Stanford Epidemiology and Population Health Department

Farrar named CEO at Ohio State James Cancer Hospital and Solove Research Institute

Yang appointed director of Division of Hematology at Ohio State

Patierno receives AACR Distinguished Lectureship on the Science of Cancer Health Disparities

Samuel Waxman Cancer Research Foundation awards $1.4 million in grants

Purdue and Frederick National Laboratory form partnership focused on big data approach to cancer

Bauml, Lai, and Lisberg receive LUNGevity 2019 Career Development Awards

UMN researchers awarded grant in metastatic breast cancer

Fortin departs Winship for UCLA Health

Clinical Roundup

IMFINZI is first immunotherapy to show OS benefit, improved, durable responses in extensive-stage SCLC

Pooled five-year survival results show OS advantage for Opdivo in advanced NSCLC

LOXO-292 shows 68% ORR, sustained durability in heavily pretreated RET fusion-positive NSCLC

ASTRO guideline clarifies role of radiation therapy in pancreatic cancer treatment

Study shows higher risk of death in patients with CV conditions who receive novel oral prostate cancer therapies

Drugs & Targets

Adaptimmune receives Orphan Drug Designation for SPEAR T-cells targeting MAGE4-A in soft tissue sarcoma

BioXcel receives Orphan Drug Designation for BXCL701 in AML

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