Alexander Price named assistant professor at Wistar

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Alexander Price

Alexander Price was named assistant professor in the Gene Expression and Regulation Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute.

Price’s research focuses on how viral genomes are controlled during infection—specifically, how viruses regulate and exploit RNA transcription and processing. His work aims to identify and exploit therapeutic targets underlying how viruses hijack cellular transcriptional machinery to combat disease.

“We are immensely pleased to welcome Alex Price to Wistar. The Institute is committed to expanding our understanding of viruses’ role in cancer as well as other disease, and the establishment of the Price Lab at Wistar represents a significant investment in the Institute’s research capacity,” Dario Altieri, Wistar president and CEO, director of the Ellen and Ronald Caplan Cancer Center, and the Robert and Penny Fox Distinguished Professor, said in a statement. “Alex’s experience in viral RNA and DNA research makes it clear that he will make compelling, fresh contributions to Wistar’s research program.”

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The Wistar Institute’s president and CEO, Dario C. Altieri, and his team have demonstrated the role of Parkin—a protein implicated in Parkinson’s disease—in the body’s innate immune response to cancer. Parkin is not expressed in several cancers. Altieri and his team engineered cancer cells to re-express Parkin and found that Parkin contributes to the production of interferons, which activate and attract T cells to fight the tumor. The lab’s findings were published in The Journal of Clinical Investigation.

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