Myles Brown is the recipient of the 2019 AACR Distinguished Lectureship in Breast Cancer Research award at the San Antonio Breast Cancer Symposium, and Celina Kleer will receive the 2019 American Association for Cancer Research Outstanding Investigator Award for Breast Cancer Research at the symposium.
The Distinguished Lectureship is supported by Aflac Inc. Outstanding Investigator award is
supported by the Breast Cancer Research Foundation.
Brown, the Emil Frei III Professor of Medicine at Dana-Farber Cancer Institute and Harvard Medical School, is being recognized for his research on steroid receptor-coregulators that has put a spotlight on the dynamic ability of these proteins to regulate the genome. His research has elucidated the epigenetic factors underlying the action of steroid hormones and effectively shaped understanding of the role of nuclear hormone receptors in normal physiology and breast cancer. Brown will deliver a lecture Dec. 12, at 11:30 a.m., “Essential genes and cistromes in breast cancer.”
Kleer, the Harold A. Oberman Collegiate Professor of Pathology at the University of Michigan Medical School and Rogel Cancer Center, is being recognized for her work generating key insights into the development of aggressive forms of breast cancer and for advancing the characterization of clinical biomarkers and potential therapeutic targets for these cancer subsets.
Kleer’s research led to the initial demonstration of EZH2 overexpression in metastatic hormone receptor negative breast cancer and the elucidation of molecular determinants of metaplastic breast carcinoma. Kleer will present a lecture on Dec. 13 at 11:30 a.m., “Novel non-canonical functions of EZH2 in triple negative breast cancer.”
The 2019 SABCS will be held Dec. 10-14 at the Henry B. González Convention Center in San Antonio.
