Issue 3 - Jan 20, 2017
  • “Will I still have coverage?” patients ask oncologists as Republicans move to gut Affordable Care Act

    As Congress lays down the groundwork for dismantling the Affordable Care Act, doctors across America are hearing cancer patients speak of their fear of losing access to care if the law known as “Obamacare” is jettisoned without replacement.

  • FDA forms Oncology Center of Excellence, names Richard Pazdur director

    On his last full day as FDA commissioner, Robert Califf announced the formation of the Oncology Center of Excellence and named Richard Pazdur its director.

    The process of forming the center began in June, and Pazdur has been the acting director. Reorganization of the FDA oncology portfolio is an element of the Obama White House Moonshot Initiative.

  • Guest Editorial

    NCI formulary, moonshot and public-private partnerships

    Announcing the NCI Formulary, the Jan. 13 issue of The Cancer Letter includes comments suggesting the road to new therapies will now get “easier” and other comments indicated that industry and/or NCI collaborators will “not provide support other than drug access”.

  • In Brief

    • Richard Goldberg new director of West Virginia University Cancer Institute
    • Justin Klamerus named president of Karmanos Cancer Hospital
    • Werner-Wasik new executive vice chair, radiation oncology integration at Jefferson
    • Northwell Health partners with Indivumed to create cancer research biobank
    • Tempus and University Hospitals/Seidman announce effort to customize treatment
    • Reporting of lung cancer surgery outcomes provides info about quality of care
  • Drugs & Targets

    • Medicinal product designation for TB-403 for medulloblastoma
  • Funding Opportunities

    LUNGevity issues RFA for career development award

    LUNGevity announced a request for applications for translational research for career development awards that will be granted in 2017.

Issue 2 - Jan 13, 2017
  • NCI develops a “formulary” to make it easier for cancer centers to test drug combinations

    With a simplified tech transfer agreement, six industry partners and 15 compounds (but no dedicated research funds), NCI challenges investigators to think creatively.

  • Conversation with The Cancer Letter

    Simon: The moonshot will continue, but the electronic health record industry must step up

    The National Cancer Moonshot Initiative was created by a memorandum issued by President Barack Obama.

    The wide-ranging public health initiative will cease to exist on Jan. 20—eight days short of a year after it was created—when the keys to the White House are handed over to Donald Trump.

  • In Brief

    • Sakaguchi, Ramsdell, Rudensky win Crafoord Prize for discoveries in immune regulation
    • Gustavo Leone named director of  MUSC Hollings Cancer Center
    • Levine Cancer Institute is first to earn top designation for patient-centered care
    • Martin Edelman joins Fox Chase as hematology/oncology chair
    • Diane Simeone to lead pancreatic cancer center at NYU Langone
    • Mario Contreraz named administrator of IU cancer center clinical trials office
    • Columbia, NewYork-Presbyterian and Life Raft form GIST research partnership
    • NCCN publishes patient education resources for gliomas
    • NIHCM Foundation awards $345K in investigator-initiated research grants
    • LUNGevity Foundation introduces mobile app to help patients manage lung cancer
    • NPR station broadcasts anniversary program on moonshot
    • Goldberg novel is finalist in Jewish Book award
  • Drugs & Targets

    • Merck joins ORIEN
    • Scripps to collaborate with Pfizer to advance DNA-encoded library technology
    • AbbVie announces four new global research collaborations
    • Lilly and Merck expand immuno-oncology collaboration
    • Amgen and Immatics collaborate to develop cancer immunotherapies
    • Philips and Illumina to co-develop integrated genomics solutions for oncology
    • Tecentriq receives priority review for treatment of urothelial carcinoma
    • EMD Serono and MD Anderson enter three-year collaboration
    • MD Anderson and Deerfield Management create company to inhibit autophagy
    • Cologuard earns positive review from Blue Cross Blue Shield Association
    • FDA accepts BLA for Mylan and Biocon’s biosimilar Trastuzumab
    • FDA releases guidance on nonproprietary naming of biologics
Issue 1 - Jan 6, 2017
  • Doug Lowy on the moonshot, NCI’s invigorated agenda

    As administrations change, cancer research stands in an unusually strong position, NCI Acting Director Douglas Lowy said in an interview with The Cancer Letter.

    “We’re very fortunate that both Republicans and Democrats strongly support biomedical research in general, and cancer research in particular,” Lowy said in a wide-ranging interview. “The leadership of the House and Senate appropriations subcommittees was responsible for the increase in FY16 for the NIH appropriation.”

  • MD Anderson lays off 900 staff members

    The year got off to a bad start for some employees of MD Anderson
    Cancer Center.

    As part of a cost-cutting measure announced Jan. 5, about 900 of them received layoff notices.

    Television crews crowded the parking garages of the Houston hospital, capturing images of teary-eyed people carrying boxes to their cars.

  • Biden plans to create moonshot nonprofit, may focus on drug prices

    After leaving the White House, Vice President Joe Biden plans to consolidate his work on the Cancer Moonshot into an independent, nonprofit organization, while juggling non-cancer programs at two universities.

    Biden aims to continue work on the National Cancer Moonshot Initiative through a new nonprofit that will not be connected to any cancer center or university, according to sources familiar with Biden’s post-administration goals.

  • Introducing a redesign of  The Cancer Letter

    Dear Reader,

    The Cancer Letter is starting 2017 with something we haven’t done in …
    well, ever.

  • In Brief

    • Chi Van Dang named scientific director of Ludwig Institute
    • Vacirca elected COA president
    • Ruckdeschel heads cancer institute at University of Mississippi Medical Center
    • Cassels retires as chief administrator at Winship
    • ACS names three new members to board
    • Kratzke, O’Regan chosen to leadership roles at Big Ten consortium
    • PCORI approves $42 million in funding for comparative studies on healthcare approaches
  • Drugs & Targets

    • AACR project GENIE releases cancer genomic data set
    • Strata Trial study launched with UNC, Alabama cancer centers
    • Foundation Medicine receives FDA approval as companion diagnostic
    • Ionis gets $28 million from AstraZeneca for new cancer drug
    • MaxCyte, Washington University in St. Louis announce collaboration
    • MD Anderson, Affimed collaborate on immunotherapy combination
    • Gradalis, Mount Sinai announce research alliance
    • Phylogica, Genentech extend agreement
    • Senhwa gets FDA orphan drug designation
    • Oncotype DX included in AJCC staging criteria
  • Funding Opportunities

    Addario foundation, IASLC announce grant

    The Bonnie J. Addario Lung Cancer Foundation and the International Association for the Study of Lung Cancer announced the second annual joint fellowship award to support research on the early detection of lung cancer.