Issue 27 - Jul 6, 2018
Issue 26 - Jun 29, 2018
  • Senate committee proposes $2 billion raise for NIH, signaling fourth good year in a row

    When the Senate Committee on Appropriations marked up the fiscal 2019 spending bill, NIH came out ahead—$2 billion ahead.

  • NCI Director’s Report

    What NCI did with the money: Sharpless boosts funding for RPGs, centers, SPOREs, NCTN, and NCORP

    In addition to a $147 million increase to the Research Grant Project pool, NCI has added $60 million to targeted research opportunities and a $20 million increase for centers and SPOREs, and $10 million for the National Clinical Trials Network and the NCI Community Oncology Research Program.

  • Turkish oncologist Murat Tuncer jailed

    A. Murat Tuncer, a pediatric oncologist and former rector of Hacettepe University, has spent the past two months in a very uncomfortable place—the Sincan Prison in Ankara.

  • In Brief

    • Case Comprehensive Cancer Center earns “exceptional” rating, $31.9M in NCI grants
    • UPMC to advise cancer treatment center in Beijing
    • UPMC and Pitt open genome center for precision medicine, immunotherapy
    • MSKCC expands its presence in Northern New Jersey
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  • Clinical Roundup

    • Lynparza delays disease progression in phase III trial in first-line ovarian cancer
    • Tecentriq + chemo increase OS, PFS in untreated extensive stage small cell lung cancer
    • Trifluridine and tipiracil meet OS endpoint in phase III trial
    • ONS develops hazardous drugs safe handling toolkit for oncology nurses
  • Drugs & Targets

    • FDA approves Braftovi + Mektovi combination in a melanoma indication
    • Kymab, Roche agree to evaluate KY1044, anti-PD-L1 immunotherapy in solid tumors
    • FDA grants orphan drug designation for CPI-613 for Burkitt lymphoma
  • CTEP Protocol

    NCI Trials for June

    The National Cancer Institute Cancer Therapy Evaluation Program approved the following clinical research studies last month.

    For further information, contact the principal investigator listed.

Issue 25 - Jun 22, 2018
  • Vinay Prasad, oncologist and Twitter star, locked in debate over precision medicine

    In recent years, Vinay Prasad, a young hematologist–oncologist at Oregon Health and Science University, has emerged as a premier critic of new directions in cancer medicine.

    In his view, cancer drugs are aimed at miniscule populations, approved way too easily, and priced too high.

  • Reviews of Prasad’s “thought experiment”

    As a reporter, I have no standing in settling scientific disputes.

    So, when Vinay Prasad and I hit the wall in our discussion of the assumptions he and a group of colleagues made in their provocative “thought experiment,” I decided to do what journals do—send the paper to peer reviewers.

  • Conversation with The Cancer Letter

    Prasad: FDA has confused merely approving drugs with making the world a better place

    have been following Vinay Prasad’s work for several years, agreeing with some of what he said, but never quite finding time to look carefully at his argumentation.

  • In Brief

    • Norman Coleman, Gay Crawford to receive NCCS Stovall Award for advancing patient-centered care
    • Marc Lippman, breast cancer expert, returns to Georgetown Lombardi
    • Laura Hutchins named interim director of UAMS Rockefeller Cancer Institute
  • Funding Opportunity

    DOD Prostate Cancer Research Program opportunities

    The FY18 Defense Appropriations Act provides $100 million to the Department of Defense Prostate Cancer Research Program to support innovative, high-impact prostate cancer research.

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  • Clinical Roundup

    • Kymriah shows more than one-year durable responses in relapsed or refractory DLBCL
    • Lonsurf improves OS in metastatic gastric cancer
    • Greater levels of vitamin D associated with decreasing risk of breast cancer
    • Diabetes diagnosis later in life may signal early pancreatic cancer in African-Americans and Latinos
    • Study finds emergency colon cancer surgery performed on weekends more likely to lead to complications
  • Drugs & Targets

    • FDA to review BRACAnalysis CDx sPMA as companion diagnostic for Talazoparib
    • China’s drug agency approves Opdivo for previously treated NSCLC
    • Natera, Institut Jules Bordet to collaborate on neoadjuvant breast cancer assay