NCI CTEP-Approved Trials for the Month of November

The National Cancer Institute Cancer Therapy Evaluation Program approved the following clinical research studies last month. For further information, contact the principal investigator listed.

Phase II

9598: A Phase II Therapeutic Trial of the Use of Dabrafenib and Trametinib in Patients with BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease. National Institutes of Health; Estrada-Veras, Juvianee Ibrahim. (301) 594-2952

9653: Phase II Trial of Gemcitabine-Eribulin (GE) in Cisplatin Ineligible Patients with Advanced or Unresectable Urothelial Carcinoma of the Bladder. University of California Davis Comprehensive Cancer Center P2C; Sadeghi, Sarmad. (323) 865-0553

9880: Haploidentical Donor Natural Killer (NK) Cell Infusion with Subcutaneous Recombinant Human IL-15 (rhIL-15) in Adults with Refractory or Relapsed Acute Myelogenous Leukemia. University of Minnesota Medical Center-Fairview; Miller, Jeffrey Steven (612) 624-0123

NRG-BN001: Randomized Phase II Trial of Hypofractionated Dose-Escalated Photon IMRT or Proton Beam Therapy Versus Conventional Photon Irradiation with Concomitant and Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma. NRG Oncology; Mehta, Minesh P. (410) 328-9629

NRG-HN002: A Randomized Phase II Trial for Patients with p16 Positive, Non-Smoking Associated, Locoregionally Advanced Oropharyngeal Cancer. NRG Oncology; Yom, Sue Sun (415) 353-7410

Other Phases

A151315: An Analysis of Baseline Serum NTx and BAP as Independent Predictors of Overall Survival and Risk of SREs. Alliance for Clinical Trials in Oncology; Saylor, Philip James. (617) 643-1763

ECOG-E2197F-ECOG-ICSC: Tumor MicroEnvironment of Metastasis (TMEM) and MenaCalc: Validation as Prognostic and Predictive Markers. ECOG-ACRIN Cancer Research Group; Sparano, Joseph Anthony (718) 904-2555

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NCI CTEP-Approved Trials for the Month of November

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The Directors: Candace Johnson and Jonathan Friedberg on living through uncertainty at NCI, payment woes
Directors of two neighboring cancer centers in Upstate New York will face challenges, but “we’ll get through it”

Senators slam Bhattacharya for deflecting responsibility for NIH cuts, upheaval
Susan Collins: Trump’s 40% cut is “so disturbing”

In first NCAB meeting since Trump’s inauguration, Lowy reflects on funding choices in lean times
“In the NCI director’s office, we have a photograph of a stone bridge, and it asks the question, which stone holds up the bridge? And the answer is all of them.”

CRC patients with cannabis use disorder may have higher odds of death within five years of diagnosis
Observational study suggests that clinicians should be cautious when recommending cannabis to manage cancer symptoms

Insights from ASCO 2025: Real-world evidence drives clinical decision-making

The Cancer Letter receives nine journalism, design awards

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NCI CTEP-Approved Trials for the Month of November

YOU MAY BE INTERESTED IN

The Directors: Candace Johnson and Jonathan Friedberg on living through uncertainty at NCI, payment woesDirectors of two neighboring cancer centers in Upstate New York will face challenges, but “we’ll get through it”

Senators slam Bhattacharya for deflecting responsibility for NIH cuts, upheavalSusan Collins: Trump’s 40% cut is “so disturbing”

In first NCAB meeting since Trump’s inauguration, Lowy reflects on funding choices in lean times“In the NCI director’s office, we have a photograph of a stone bridge, and it asks the question, which stone holds up the bridge? And the answer is all of them.”

CRC patients with cannabis use disorder may have higher odds of death within five years of diagnosisObservational study suggests that clinicians should be cautious when recommending cannabis to manage cancer symptoms

Insights from ASCO 2025: Real-world evidence drives clinical decision-making

The Cancer Letter receives nine journalism, design awards

Never miss an issue!

Login

The Directors: Candace Johnson and Jonathan Friedberg on living through uncertainty at NCI, payment woes
Directors of two neighboring cancer centers in Upstate New York will face challenges, but “we’ll get through it”

Senators slam Bhattacharya for deflecting responsibility for NIH cuts, upheaval
Susan Collins: Trump’s 40% cut is “so disturbing”

In first NCAB meeting since Trump’s inauguration, Lowy reflects on funding choices in lean times
“In the NCI director’s office, we have a photograph of a stone bridge, and it asks the question, which stone holds up the bridge? And the answer is all of them.”

CRC patients with cannabis use disorder may have higher odds of death within five years of diagnosis
Observational study suggests that clinicians should be cautious when recommending cannabis to manage cancer symptoms