MURANO, a randomized phase III study sponsored by Abbvie, showed that patients with relapsed or refractory chronic lymphocytic leukemia achieved significantly prolonged median progression-free survival with Venclexta/Venclyxto (venetoclax) in combination with Rituxan (rituximab) [median PFS, not reached], compared with bendamustine in combination with Rituxan [median PFS, 17.0 months; hazard ratio, 0.17; 95% CI, 0.11–0.25; P<0.0001].
Juno Therapeutics Inc., a biopharmaceutical company developing cellular immunotherapies for the treatment of cancer, released additional data from the TRANSCEND study of JCAR017 (lisocabtagene maraleucel; liso-cel) in patients with relapsed or refractory aggressive B-cell non-Hodgkin lymphoma in a presentation at the 59th American Society of Hematology Annual Meeting and Exposition.
The phase III EMBRACA trial in patients with germline BRCA1/2-positive locally advanced and/or metastatic breast cancer demonstrated superior progression-free survival in patients treated with talazoparib, compared to patients who received physician's choice standard of care chemotherapy.
Lefkofsky spoke with Paul Goldberg, editor and publisher of The Cancer Letter.
Hudis spoke with Paul Goldberg, editor and publisher of The Cancer Letter.
The American Society of Clinical Oncology has reached a deal that will allow two companies—Tempus and Precision Health AI—to curate and license the data in CancerLinQ, the professional society's venture into Big Data.
In 2017, The Cancer Letter's readership grew by over 40 percent and the number of page views has nearly doubled from the 2016 level.
About one in 225 to one in 580 women who undergo surgery for fibroids may have hidden uterine cancers, FDA concluded in a recent review of medical studies published over the past four years.
Five health care systems have joined a precision oncology network that sequences patients' tumors at no cost and matches patients to clinical trials.
In his first talk to NCI staff, director Norman “Ned” Sharpless presented himself as an institute insider—highlighting his career-long relationships with NCI and its “legends,” demonstrating his grasp of the institute's agenda and research portfolio.
