The Cancer Letter

Lung-MAP: A five-year recap on the first master protocol trial in cancer research
FreeGuest Editorial

Lung-MAP: A five-year recap on the first master protocol trial in cancer research

When the Lung-MAP trial was launched in June 2014, the goal was simple: Make drug development faster and more collaborative—and do it for lung cancer, the leading cause of cancer death in the United States.This is a formidable challenge. Cancer trials were, and remain, notoriously time-consuming to launch, expensive to run, and difficult to enroll patients to. A deeper understanding of cancer biology and the genomics revolution in medicine have changed how we approach clinical research.When the Lung-MAP trial was launched in June 2014, the goal was simple: Make drug development faster and more collaborative—and do it for lung cancer, the leading cause of cancer death in the United States.
NCI’s Penberthy: We may be seeing some impact of treatment in lung cancer mortality, but we need more data
Conversation with The Cancer Letter

NCI’s Penberthy: We may be seeing some impact of treatment in lung cancer mortality, but we need more data

If the mortality rate for lung cancer is starting to fall of a cliff in part because of treatment effect—contributing to more than a third of the 2.2% decline in overall cancer mortality from 2016 to 2017—is that signal showing up on the radar of NCI's Surveillance, Epidemiology, and End Results (SEER) Program?