Intratumoral delivery of an engineered oncolytic virus, DNX-2401, targeting glioblastoma cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional phase I/II clinical trial co-led by researchers at MD Anderson Cancer Center and the University of Toronto.
Women with early-stage cervical cancer had significantly higher chances of developing catheter-associated urinary tract infections after radical hysterectomies if they were smokers or used a catheter for more than seven days post-surgery, UT Southwestern Medical Center researchers found in a study.
Results from a phase I trial at Memorial Sloan Kettering Cancer Center suggest that treatment with mRNA vaccines (autogene cevumeran) cause an effective and lasting immune response in some patients with pancreatic cancer.
Researchers at the American Cancer Society, in an analysis of cancer death rates across all congressional districts in the U.S., found an overall decline in the past 25 years, with most districts showing a 20%-45% decline among males and a 10%-40% decline among females.
A recent clinical trial demonstrated that the drug combination of cemiplimab plus platinum chemotherapy can prolong survival in patients with advanced lung cancer when compared with placebo plus platinum chemotherapy.
Immigrant adults with liver cancer in the U.S. have higher survival rates than people with the disease who were born in the U.S., according to research from the USC Norris Comprehensive Cancer Center.
Research led by UC Davis Comprehensive Cancer Center reveals a link between bone metabolism biomarkers and survival in men with newly diagnosed hormone-sensitive prostate cancer who received androgen deprivation therapy.
A Fred Hutchinson Cancer Center study, published in Obstetrics & Gynecology,investigated how endometriosis, uterine leiomyomas (also known as fibroids), and a common intervention for these conditions—hysterectomy—changed ovarian cancer risk in Black and white women.
Researchers at the UNC Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center found mailing human papillomavirus self-collection tests and offering assistance to book in-clinic screening appointments to under-screened, low-income women improved cervical cancer screening nearly two-fold compared to scheduling assistance alone.
SpaceMarkers, a machine learning software developed by researchers at the Johns Hopkins Convergence Institute and the Johns Hopkins Kimmel Cancer Center, can identify molecular interactions among distinct types of cells in and around a tumor, according to a study published in Cell Systems.
