The majority of patients eligible for cancer immunotherapy drugs known as checkpoint inhibitors received treatment within a few months of FDA approval, according to a new Yale-led study.
In a phase III trial of Lonsurf (trifluridine and tipiracil) plus best supportive care versus placebo plus BSC in patients with previously treated metastatic gastric cancer, the Lonsurf-containing arm met the primary endpoint of prolonged overall survival.
According to the Oncology Nursing Society's new position statement, “Role of the Oncology Nurse Navigator Throughout the Cancer Trajectory,” oncology nurse navigators are crucial to the successful outcomes of patients with cancer. Through clinical expertise, care coordination skills, and leadership abilities, ONNs are able to guide their patients during the cancer trajectory.
Merck said the pivotal phase III KEYNOTE-407 trial investigating Keytruda (pembrolizumab), Merck's anti-PD-1 therapy, in combination with carboplatin-paclitaxel or nab-paclitaxel as first line treatment for metastatic squamous non-small cell lung cancer met a pre-specified secondary endpoint of overall response rate in an early cohort of participants at an interim analysis.
TESARO Inc. said the QUADRA study of Zejula treatment in heavily pre-treated patients with ovarian cancer achieved the pre-specified primary endpoint and demonstrated Zejula monotherapy activity in a biomarker-selected patient population.
Merck announced results from KEYNOTE-189, a pivotal phase III trial evaluating Keytruda (pembrolizumab) in combination with pemetrexed (Alimta) and cisplatin or carboplatin for the first-line treatment of metastatic nonsquamous non-small cell lung cancer.
Merck and the European Organisation for Research and Treatment of Cancer announced findings from the phase III EORTC1325/KEYNOTE-054 trial investigating Keytruda (pembrolizumab) as adjuvant therapy in resected, high-risk stage III melanoma.
An immunotherapy administered prior to surgery is yielding outcomes in 45% of patients treated in this small study from researchers on the Stand Up to Cancer-Cancer Research Institute Cancer Immunology Dream Team, who is a scientific partner of Stand Up to Cancer, according to results presented at the American Association for Cancer Research Annual Meeting. It was published online in The New England Journal of Medicine.
In a new study, researchers identified genetic subtypes of diffuse large B-cell lymphoma that could help explain why some patients with the disease respond to treatment and others don't.
The American Society for Radiation Oncology issued an update to its clinical guideline for the use of palliative-intent radiation therapy for patients with incurable non-small cell lung cancer.
