TESARO Inc. announced the presentation of maturing data from the TOPACIO trial of Zejula (niraparib) in combination with Keytruda (pembrolizuma) during a plenary session at the 2018 Society for Gynecologic Oncology Annual Meeting on Women's Cancer in New Orleans.
A retrospective analysis of the phase III NOVA trial identified two baseline characteristics, patient body weight less than 170 pounds (77 kilograms) or platelet count of <150,000/µL to be significant factors for grade III or IV thrombocytopenia.
Array BioPharma Inc. published the results of its phase III COLUMBUS trial for the treatment of patients with BRAF-mutant advanced, unresectable or metastatic melanoma were published in The Lancet Oncology.
AVEO Oncology has published the long-term follow-up results from Study 902, where patients were treated with tivozanib (Fotvda) as second-line treatment in advanced renal cell carcinoma, in the European Journal of Cancer. The publication, titled “Efficacy of Tivozanib Treatment after Sorafenib in Patients with Advanced Renal Cell Carcinoma: Crossover of a Phase 3 Study”, was published online first and is available here.
Men who take the medication finasteride get a prostate cancer prevention benefit that can last 16 years—twice as long as previously recorded, according to SWOG clinical trial analysis published in the Journal of the National Cancer Institute.
Researchers at Emory University and Northwestern University developed artificial intelligence software that can predict the survival of patients diagnosed with glioma by examining data from tissue biopsies.
The American Society for Radiation Oncology issued a clinical guideline for the use of whole breast radiation therapy for breast cancer that expands the population of patients recommended to receive accelerated treatment known as hypofractionated therapy.
A newly-published study shows many remain at risk for later complications from chemotherapy or other treatments. The study in the Journal of the National Comprehensive Cancer Network confirms testicular cancer survivors are more likely to develop high blood pressure, high cholesterol, and obesity, which can significantly increase their risk of heart disease.
Using data from a large ovarian cancer registry, a research team from Roswell Park Comprehensive Cancer Center uncovered a link between testicular cancer and familial ovarian cancer that may be attributable to genetic factors on the X chromosome.
The National Comprehensive Cancer Network has released a new NCCN Clinical Practice Guidelines in Oncology intended to help make sure people living with HIV who are diagnosed with cancer receive safe, necessary treatment.
