Clinical Roundup

Clinical Roundup

Intervention eliminates Black-white gaps in survival from early-stage breast and lung cancer

The Accountability for Cancer Care through Undoing Racism and Equity (ACCURE) clinical trial—a prospective study designed to reduce gaps in cancer treatment completion and survival among Black and white patient populations— found that identifying and addressing obstacles that kept patients from finishing radiation treatments improved five-year survival rates for all patients and erased the survival gap between Black and white patients.
Clinical Roundup

Imfinzi + tremelimumab significantly improved OS for 1st-line unresectable liver cancer in HIMALAYA phase III trial

A single, high priming dose of tremelimumab added to Imfinzi (durvalumab) demonstrated a statistically significant and clinically meaningful overall survival benefit versus Nexavar (sorafenib) as a first-line treatment for patients with unresectable hepatocellular carcinoma who had not received prior systemic therapy and were not eligible for localized treatment. 
Clinical Roundup

EXALT-1 trial shows benefit of AI-supported functional precision medicine platform in late-stage hematological cancer

Researchers from Exscientia, the Medical University of Vienna, and the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences demonstrated the impact of using Exscientia’s AI-supported precision medicine platform to propose which therapy would be most effective for late-stage hematological cancer patients, based on testing drug responses ex vivo in their own tissue samples.