publication date: Oct. 24, 2014
20141024 - Oct. 24, 2014
ISSUE 40 – OCT. 24, 2014PDF



40 Years Later
Doctor and Patient Reflect on the Cure

On Oct. 21, 1974, John Cleland lay in a hospital bed at Indiana University Hospital.

At 23, he had just graduated from Purdue University and just married.

He was also three weeks into a fourth-line chemotherapy regimen for advanced metastatic testicular cancer. The disease had spread to his lungs.

Lawrence Einhorn, Cleland’s doctor, told him that this was the end of the road.

Conversation with The Cancer Letter
Einhorn: “I Still Harbor Hope For Similar Success Stories”

The Cancer Letter asked Lawrence Einhorn, distinguished professor of medicine and the Livestrong Foundation Professor of Oncology at the Indiana University Melvin and Bren Simon Cancer Center, to reflect on one of the most spectacular successes in the history of cancer research—his development of the curative regimen for testicular cancer.

Caris Life Sciences Lays Off Estimated 20 Percent of Staff

Caris Life Sciences Inc. last week reduced its workforce by 50 people—about 20 percent, sources said.

While a 50-person reduction in force is small by pharma industry standards, the development could be significant because Caris is a key player in the emerging market for molecular therapies.

HRSA: Discounts Owed on Some Orphan Drug Uses

The Health Resources and Services Administration last week warned pharmaceutical companies that they must continue to offer 340B Drug Pricing Program discounts on some uses of orphan drugs.

Cancer Support Community Reports on Patient Experiences

Cancer Support Community released the findings report from the first year-and-a-half of the Cancer Experience Registry.

Institute of Medicine Elects 80 New Members

The Institute of Medicine named 70 new members and 10 foreign associates during its 44th annual meeting.

New members are elected by current active members through a selective process that recognizes individuals who have made major contributions to the advancement of the medical sciences, health care, and public health.

photoIn Brief

  • Benjamin Neel named director of NYU Cancer Center

  • Brad Pollock named chair of public health department at UC Davis

  • Richard Zellars named chair of radiation oncology at IU School of Medicine

  • David Mauro named chief medical officer and VP of Advaxis Inc.

  • James Tulsky receives award from American Cancer Society

  • Mary Kozik named senior director of development at Winship Cancer Institute

  • Northwestern Mutual and Alex’s Lemonade Stand fund eight young investigators

  • Association of Community Cancer Centers receives gift from Bristol-Myers Squibb

  • Stand Up To Cancer epigenetics dream team receives $7.5 million from Van Andel Research Institute

photoDrugs and Targets

  • EU approves Imbruvica in MCL, CLL

  • CMS publishes two draft coverage determinations for molecular prostate cancer tests

  • Priority Health to cover FoundationOne genomic profiles

  • Celgene and Sutro Biopharma to collaborate on antibody-drug conjugates

Copyright (c) 2020 The Cancer Letter Inc.