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Issue 11 - Mar 17, 2017

TCL43-11 (2473 downloads)

Trump’s proposed 2018 budget launches a surprise attack on NIH
FDA may have escaped the devastating cuts in President Trump’s first budget proposal, while NIH ended up taking the brunt of its fury.
White House “vision” would cripple NIH
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Conversation with the Cancer Letter
John Porter: If you want to make America great, you don’t take America’s worldwide scientific lead and cut it
As former chairman of the Appropriations Subcommittee on Labor, Health and Human Services, Education, and Related Agencies, then-Rep. John Porter (R-IL) oversaw the doubling of the NIH budget over five years.
Conversation with the Cancer Letter
Nancy Davidson: This is the time for investment, not for retreat
First, Congress should follow through on increasing the NIH budget by $2 billion in fiscal 2017, said Nancy Davidson, president of the American Association for Cancer Research.
Second, the House and the Senate should craft appropriations bills that will provide robust, sustainable, and predictable increases for fiscal 2018, said Davidson, executive director and president at Seattle Cancer Care Alliance, senior vice president and director of the Clinical Oncology Division at Fred Hutchinson Cancer Research Center, and professor and Head, Division of Medical Oncology at the University of Washington School of Medicine.
Conversation with the Cancer Letter
Ellen Sigal: This is not a grasstops issue anymore, this is really grassroots
Over decades, Ellen Sigal has emerged as a Washington insider in oncology, someone who has the ability to convene key players in academia, industry and government.
Conversation with the Cancer Letter
Blase Polite: This was put together by folks who have no sense of how research is done
If Congress follows the fiscal 2018 budget priorities outlined by the White House, the United States will lose its standing as the powerhouse of biomedical research, said Blase Polite, chair of the American Society of Clinical Oncology Government Relations Committee.
Conversation with the Cancer Letter
Patricia Goldsmith: This is the “Moonstab,” or, maybe, the “Moonshaft”
Coupled with the repeal of the Affordable Care Act, the administration’s proposed cuts to the NIH budget would be devastating for cancer patients, said Patricia Goldsmith, CEO of CancerCare, an organization that provide counseling, support groups, education, and financial assistance.
“Duplicity” at NIH?
White House spokesman Sean Spicer says the cut isn’t really a cut
White House spokesman Sean Spicer said the cuts proposed by the administration will help eliminate inefficiency and duplication at NIH. At a White House press briefing March 16, Spicer was asked to justify his boss’s proposal to gut biomedical research funding.
Beth Caldwell: People like me will die because of these cuts
Beth Caldwell, a patient with metastatic neuroendocrine breast cancer, has more to lose than anyone else in the controversy over President Donald Trump’s proposed cuts to the NIH budget.
In Brief
- Marshall Hicks named interim president of MD Anderson Cancer Center
- Stupp named associate director, strategic initiatives at Lurie Cancer Center
- City of Hope vice provost to focus on faculty growth initiatives
- Nichols named LLS chief medical officer
- Penson named chair of Science & Quality Council at American Urological Association
- NCI selects ATCC to provide end-to-end cancer epidemiology services
- ILO delays vote on whether to cut ties with tobacco industry
Drugs and Targets
- Kisqali gets FDA approval as first-line treatment for HR+/HER2- metastatic breast cancer in combination with any aromatase inhibitor
- Keytruda gets accelerated approval for classical Hodgkin lymphoma
- FDA extends Keytruda PDUFA date for microsatellite instability-high cancer
- Mylan announces settlement, license deals with Genentech and Roche on Herceptin
- Oncoceutics expands DRD2 research collaborations with NIH

Issue 10 - Mar 10, 2017

TCL43-10 (333 downloads)

DePinho resigns as MD Anderson president, acknowledges shortcomings as administrator
Ronald DePinho announced on March 8 that he will be stepping down as president of MD Anderson Cancer Center.
DePinho’s five-and-a-half years at the helm of the world’s largest cancer center were marked by unprecedented turbulence, questions of conflicts of interest, and unhappiness on the part of the faculty.
House Republicans publish legislation for replacing Obamacare with Trumpcare
The House Republicans on March 6 published the Obamacare repeal bill, touching off predictable tidal waves of recriminations, with Democrats stating that the bill would “rip healthcare away from millions of Americans, ration care for working families and seniors, and put insurance companies back in charge of healthcare decisions”
Note to international travelers: U.S. customs can take your laptop and ask for passwords
As spring meetings get going, many cancer organizations are offering what amounts to packing tips, suggesting that some electronic devices are best left at home.
In Brief
- Lynch steps in as CSO at Bristol-Myers Squibb
- Pharma companies collaborate in NCCN’s multi-industry project
- NCCN “Just Bag It!” campaign shoots for 100 new adopters by end of conference
- Targeted Anticancer Therapies Congress becomes an annual ESMO Event
- ASCO and ONS launch collaboration to advance engagement in CancerLinQ
- Siteman Cancer Center launches network with affiliation of Boone hospital
Drugs and Targets
- NICE recommends Vectibix for previously untreated metastatic colorectal cancer
- EnGeneIC receives Orphan designation for its technology in glioblastoma multiforme
- German Community of Gynecological Oncology acknowledges MammaPrint as having Level 1A clinical evidence

Issue 9 - Mar 3, 2017

TCL43-09 (1873 downloads)

Conversation with The Cancer Letter
Steve Hahn and his plan for rescuing MD Anderson
Steve Hahn didn’t apply for the job of Chief Operating Officer at MD Anderson Cancer Center. In fact, there was no COO job to apply to, and conversations that preceded the announcement of his new role took less than a week.
Medicare payment in January helps MD Anderson reduce its operating losses
MD Anderson Cancer Center reduced its year-to-date operating loss to $77.3 million in January, the fifth month of the fiscal year.
Cancer groups to Trump: FDA’s oncology division is NOT “slow and cumbersome”
FDA’s approval process for drugs is “slow and cumbersome,” President Donald Trump said in his first address to a joint session of Congress on Feb. 28.
In Brief
- Karmanos, Wayne State receive grant to conduct nation’s largest study of factors affecting African Americans with cancer
- Feldman named chief of breast surgery & surgical oncology, director of breast cancer services at Montefiore and Einstein
- Michael Rosen named chief communications officer at Pancreatic Cancer Action Network
- Open Science Prize goes to software tool for tracking viral outbreaks
- Fred Hutchinson announces Harold M. Weintraub Graduate Student Award winners
- Boehringer Ingelheim, Vanderbilt expand collaboration to tackle hard-to-treat cancers
- iKnowMed recognized as No. 1 oncology EHR by Black Book Research
- CTCA, Allscripts, NantHealth to launch clinical pathways, custom oncology treatment platform
- Blackfynn and CHOP expand partnership for data integration and analysis in pediatric brain tumors
Drugs and Targets
- FDA approves Xermelo as first and only treatment for carcinoid syndrome diarrhea
- FDA Accepts avelumab BLA for Priority Review for urothelial carcinoma
- BMS expands International Immuno-Oncology Network with addition of Columbia and MacCallum Cancer Centre
- Exelixis, BMS collaborate on late-stage combination trial in first-line RCC
- Exelixis, Roche to evaluate cabozantinib and atezolizumab in solid tumors
- Advaxis, SELLAS announce licensing agreement to develop antigen-targeting immunotherapy

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