Issue 42 - Nov 8, 2019
Issue 41 - Nov 1, 2019
  • An Appreciation

    When Bernie Fisher refused to grovel

    Bernard Fisher had been in many a fight. He was, after all, an iconoclastic surgeon who had famously infuriated his colleagues by demonstrating that heroic surgeries in breast cancer do more harm than good.

  • Anatomy of a Scandal

    On a single day in March, Dr. Bernard Fisher of Pittsburgh, the country’s pre-eminent breast cancer researcher, saw his own career crumble, and watched helplessly as the research organization he had led through unprecedented advances in the treatment of breast cancer was abruptly shut down.

  • Added indignity: NIH labels Fisher’s papers as “SCIENTIFIC MISCONDUCT”

    The midterm elections of 1994 brought on political change that cost Dingell chairmanship of Energy & Commerce and Oversight and Investigations. He lost most of his staff, and there was no reason to continue oversight hearings of NSABP.

  • Breaking News

    Sharpless to return to NCI as Hahn gets nominated as FDA commissioner, with Giroir to serve as acting

    President Donald Trump has announced his intention to nominate Stephen M. Hahn to the position of FDA commissioner Nov. 1.

  • In Brief

    • Robert Winn named director of VCU Massey Cancer Center
    • Myles Brown, Celina Kleer to receive awards at San Antonio Breast Cancer Symposium
    • Brian Rini joins Vanderbilt-Ingram as chief of clinical trials
    • NCI awards UCLA prostate cancer SPORE $8.7M
    • Johns Hopkins opens proton center at Sibley Memorial Hospital
    • Allyson Kinzel named senior vice president and chief legal officer at MD Anderson
    • James Kochenderfer receives Foundation for the NIH Awards 2019 Trailblazer Prize
    • Astellas awards $200,000 in cancer grants
  • TCCL Logo

  • Clinical Roundup

    • Study finds racial disparities in treatment of multiple myeloma patients
    • Dana-Farber and UT Southwestern study finds racial disparities in culturally competent cancer care
    • NCCN publishes guidelines on managing complications and improve readiness for stem cell transplants
    • Acute lymphoblastic leukemia relapses reduced by 31%, St. Jude study shows
  • Drugs & Targets

    • AACR Project GENIE begins five-year research project with $36M in industry funding
    • European Commission approves Astellas’ Xospata indication for relapsed or refractory AML
    • DA grants Cytotron Breakthrough Device Designation for breast, liver and pancreatic cancers
    • MD Anderson, Ziopharm Oncology to expand TCR-T Program
Issue 40 - Oct 25, 2019
  • NCI to extend Cancer Center Support Grant period to seven years for qualifying cancer centers

    NCI-designated cancer centers will soon be able to extend their Cancer Center Support Grant award period from five years to seven years, depending on merit at peer review, sustained exceptional progress, stability, and longevity of the cancer center.

  • Conversation with The Cancer Letter

    Ciolino: CCSG extension will give cancer centers more freedom, time, resources to increase scientific impact

    By allowing cancer centers to extend their Cancer Center Support Grant award period from five to seven years, NCI hopes to enable eligible centers to spend less time preparing for a grant renewal in favor of conducting more research and setting long-term goals.

  • Obituary

    Bernard Fisher, pioneering breast cancer researcher, dies at 101

    Bernard Fisher, a surgeon and clinical trialist who revolutionized the field of breast cancer research and all but eliminated reliance on disfiguring surgeries, died Oct. 16 at the age of 101.

  • Aberle, DuBois, Gupta, Jaffee, Mardis among new members of the National Academy of Medicine

    The National Academy of Medicine announced the election of 90 regular members and 10 international members during its annual meeting Oct. 21.

  • In Brief

    • Sleckman to lead O’Neal Comprehensive Cancer Center
    • Michael Birrer named director of  UAMS Winthrop P. Rockefeller Cancer Institute
    • Lowy, Huntsman family among recipients of AACI/CCAF awards
    • Yale Cancer Center announces leadership appointments
    • Jyoti Patel joins Lurie Cancer Center leadership
    • UA Cancer Center Receives $8.6M grant to lead NCI Clinical Trials Network
    • House drug price plan would lower costs for some cancer drugs, but is unlikely to pass in Senate
    • IAEA and St. Jude to tackle childhood cancers in developing countries
    • Aflac Cancer and Blood Disorders program receives $20 million for pediatric cancer trials
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  • Clinical Roundup

    • Phase III IMbrave150 study demonstrates improved OS + PFS in liver cancer
    • Novel imaging technology could reduce need for additional surgery after breast cancer resection
    • Why targeted immuno-oncology drugs sometimes fail
    • Antibody eradicates leukemia stem cells
    • CheckMate-9LA meets OS primary endpoint
  • Drugs & Targets

    • FDA approves indication for Zejula in advanced ovarian, fallopian tube, or primary peritoneal cancer
    • FDA approves test to identify patients eligible for treatment with Zejula in late-line Ovarian Cancer
    • European Commission approves dosing schedules for Opdivo in melanoma
    • FDA approves Fast Track designation for bemcentinib in AML indication
    • Abernethy, Shuren, issue statement on FDA breast implant labelling guidance
    • FDA grants first-ever modified risk orders to eight smokeless tobacco products