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Issue 6 - Feb. 8, 2019
TCL45-06 (700 downloads)

  • Guest Editorial

    Two singular men shared an uncommon greatness: Waun Ki Hong and John Mendelsohn

    Waun Ki Hong and John Mendelsohn were singular forces who combined to change the world of oncology and, in the process, the lives of countless trainees, faculty, patients, and families.

  • Conversation with The Cancer Letter

    NYU receives NCI Comprehensive Cancer Center designation

    The Laura and Isaac Perlmutter Cancer Center at NYU Langone Health received the Comprehensive Cancer Center designation from NCI.

  • Trump to dedicate $500M over 10 years to childhood cancer

    In his State of the Union address Feb. 5, President Donald Trump said he plans to ask Congress for $500 million over 10 years to fund pediatric cancer research—an amount Speaker of the House Nancy Pelosi (D-CA) said is insufficient.

  • In Brief

    • Foundation Medicine gets genomic profiling contract from Veterans Affairs
    • Higgins, King, Kilmer, Fitzpatrick to serve as co-chairs of House Cancer Caucus
    • NETRF announces $2.5 million research grants to treat tumors
    • Chien-Chi Lin wins $1.5M grant in pancreatic cancer
    • ADEPT System Cancer Imager wins Illinois Tech’s $1 million Nayar Prize Competition
    • Christiana’s Boman receives $900K grant for stem cell research

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  • Clinical Roundup

    • Study finds HIV+ cancer patients benefit from immunotherapy
    • High-dose radiation therapy improves long-term survival in stage IV cancers
    • Combination of Veyonda/radiotherapy delivers clinical benefits
    • Prolonged time sitting shown to increase risk of colorectal cancer

  • Drugs & Targets

    • FDA approves therapy for adult patients with blood clotting disorder
    • Pfizer given positive CHMP opinion for Vizimpro in NSCLC
    • Genentech submits sBLA for Kadcyla for breast cancer
    • Merck KGaA and GSK to co-develop immunotherapy M7824
    • FDA pursues order to bar some retailers from selling tobacco in efforts to target tobacco use by minors

  • NCI Trials

    NCI Trials for February

    The National Cancer Institute Cancer Therapy Evaluation Program approved the following clinical research studies last month. 

Issue 5 - Feb. 1, 2019
TCL45-05 (780 downloads)

  • 20-year follow-up data are in: Prostate cancer prevention works; concerns about high-grade disease dismissed

    Prostate cancer is the most common solid tumor in men. It has been estimated that 60-75 percent of men will have histologic evidence of prostate cancer during their lifetime and that 2-4 percent of men will die of the disease. African American men are at a greater risk of diagnosis and death.

  • Guest Editorial

    The Prostate Cancer Prevention Trial and nine lessons in prostate cancer medicine

    The publication by Ian M. Thompson and colleagues in last week’s New England Journal of Medicine regarding long term follow-up of patients in the NCI-sponsored Prostate Cancer Prevention Trial (PCPT) marks a good opportunity to review and reflect on the history of the trial and the past 30 years of prostate cancer medicine.

  • Real-World Evidence

    Gottlieb: FDA to expand real-world data infrastructure to enhance AI capabilities

    FDA is enhancing its ability to handle real-world evidence by training reviewers in data science via a curriculum on machine learning and artificial intelligence, said FDA Commissioner Scott Gottlieb.

  • Industry a no-show as Sens. Grassley and Wyden hold hearing on drug pricing

    Earlier this week, the Senate Committee on Finance convened what is likely to be the first in a series of hearings focused on the rising costs of prescription drugs, oncology drugs among them.

  • In Brief

    • Califano named physician-in-chief of Moores Cancer Center
    • NYU receives anonymous $75M gift to establish center for blood cancers
    • Ross Mitchell named artificial intelligence officer at Moffitt
    • Sagar Lonial awarded Gray Family Chair in Cancer at Winship
    • Silvia Formenti and Heather McArthur awarded SU2C Laura Ziskin Prize
    • Helen Heslop named by SU2C to lead ‘Dream Team’
    • Robert Prins receives grant to research brain tumor treatments
    • Johns Hopkins Greenberg Bladder Cancer Institute Awards focused on bladder cancer in women
    • ASCO names advance of the year: progress in treating rare cancers

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  • Trials & Tribulations

    Glioblastoma patient is first to receive treatment under Right to Try. Our question is Why?

    A University of California, Irvine patient with glioblastoma recently received an experimental cancer vaccine from the U.S. subsidiary of Brussels-based Epitopoietic Research Corp. (ERC-USA). While most cases of patients receiving experimental medical treatment are not particularly newsworthy, this one was.

  • Clinical Roundup

    • Study incorporates patient feedback into better cancer treatments
    • Patients getting placebo allowed to cross to Erleada as TITAN results unblinded
    • Antioxidants may enhance chemotherapy treatment for brain tumor

  • Drugs & Targets

    • Lung-MAP precision medicine trial expands
    • Alimta + Keytruda and platinum chemo for NSCLC gets FDA label expansion
    • Trovagene and PoC Capital agree to fund clinical development of onvansertib in metastatic colorectal cancer
Issue 4 - Jan. 25, 2019
TCL45-04 (871 downloads)
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