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Issue 42 - Nov. 10, 2017
  • Skip Trump builds a cancer center by the Beltway

     Should Donald “Skip” Trump look up while talking to you on the phone, he might see deer roaming in the pine forest outside his office window.

    Trump might let his gaze skim the brown granite skin of the building of his cancer center—the Inova Schar Cancer Institute—and watch the proton beam and radiation therapy center take shape.

  • Conversation with the Cancer Letter

    Trump’s plans for Inova reach across the Washington Beltway, through Virginia—and beyond

    Trying to build a cancer center in the middle of a saturated market should be difficult enough.

    Yet, preparing to face the competition from other established cancer centers across the Potomac is just one of the challenges Donald “Skip” Trump faces as CEO and executive director of the Inova Schar Cancer Institute.

  • CMS plan to slash $1.6 billion from 340B program will reduce discounts on cancer drugs

    Hospitals enrolled in the 340B program stand to lose up to $1.6 billion in Medicare Part B reimbursements through upcoming cuts to the drug pricing program, according to a final rule by the Centers for Medicare and Medicaid Services.

  • In Brief

    • WUSTL’s DiPersio receives $6 million for leukemia research
    • Hopkins researchers launch interdisciplinary effort for breast cancer
    • Gad Getz, Chuan He, and Aviv Regev win Paul Marks Prize
    • Neuroblastoma foundation awards grant to Harvard’s Malgorzata Krajewska
    • Sanford Health wins ACCC David King Award
    • Ohio State receives Press Ganey Guardian of Excellence Award
    • NCI grant will support UA research in “lung cancer stigma”
    • NCCN publishes guidelines for cancer treatment in sub-Saharan Africa
  • Drugs and Targets

    • Alecensa gets FDA approval for ALK-positive metastatic NSCLC
    • FDA approves first treatment for Erdheim-Chester Disease
    • FDA approves Adcetris for cutaneous anaplastic large cell lymphoma
    • Seattle Genetics submits sBLA for Adcetris in Hodgkin lymphoma
October 2017PDF

 

Lung cancer

Researchers confirm IASLC proposed characterization of uncertain R Status R(un), prognosis between R0 and R1

A recent study confirmed the International Association for the Study of Lung Cancer’s proposed criteria for uncertain resection margin status, R(un), in residual tumor (R) classification.

 

Breast cancer

Trastuzumab for HER-2-expressing tumors needn’t delay breast reconstruction

Treatment with trastuzumab (Herceptin/Genentech) of breast cancers that express the HER-2 protein does not increase the risk for complications at the surgical site for women who undergo immediate breast reconstruction after mastectomy.

 

Brain Cancer

Local radiation provides comparable control of brain metastases compared to surgery

An analysis led by researchers at Fox Chase Cancer Center in collaboration with the European Organization for the Research and Treatment of Cancer found that treating cancer that has metastasized to the brain with focal, high-dose radiation yields improved early results compared with surgical removal.

 

Melanoma

Cleveland Clinic study: timing of melanoma diagnosis, treatment critical to survival

 

Prostate Cancer

Pfizer, Astellas report positive results from trial of Xtandi in non-metastatic castration-resistant disease

 

Kidney Cancer

Argos Therapeutics reports interim analysis of phase III ADAPT trial

 

NCI CTEP-Approved Trials for October

 

Regulatory actions

FDA approves Kite’s CAR-T cell therapy; another win for NCI’s intramural program

  
CCL Oct 2017 - Nov. 8, 2017
Issue 41 - Nov. 3, 2017
  • Conversation with the Cancer Letter

    Peter Pisters reflects on the upcoming challenge: leading MD Anderson

    With a month to go before his Dec. 1 start date as president of MD Anderson Cancer Center, Peter Pisters reflected on the challenges that await him in Houston.

  • House appropriators push back on Trump proposal to cap NIH facilities and administrative costs at 10%

    The Trump administration should consider NIH and the biomedical research enterprise as a component of the nation’s “defense” when making budgetary decisions, said Rep. Tom Cole (R-OK), chairman of the House Appropriations Subcommittee for Labor-HHS, Education, and Related Agencies.

  • In Brief

    • Kelly McMasters named editor of Annals of Surgical Oncology
    • Focused Ultrasound Foundation receives transformative $10 million pledge
    • Cancer imaging archive at UAMS bolstered by $8.3 million NCI grant
    • Wistar, Man’s Best Friend Therapeutics collaborate on veterinary vaccine
    • Bryant Gumbel named 2017 NFL Players Association Georgetown Lombardi Award Recipient
    • Colon Cancer Alliance changes name to Colorectal Cancer Alliance
  • Drugs and Targets

    • FDA approves AstraZeneca’s Calquence for mantle cell lymphoma
    • Consortium aims to accelerate preclinical cancer drug discovery
  • Funding Opportunities

    • The FY17 Defense Appropriations Act provides $10 million to the Department of Defense Kidney Cancer Research Program to support United States Army Medical Research Acquisition Activity