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Issue 44 – Nov. 22, 2013PDF

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ASCO Vying for Big Role in Big Data

Conversation with The Cancer Letter: ASCO President Clifford Hudis

The American Society of Clinical Oncology is in the final stages of developing a request for proposals for its CancerLinQ system. The RFP is expected to be issued early in 2014.

photoBiospecimen Banks Program for NCTN

Moves Forward With Approval From BSA

As NCI digs out after the two-week shutdown of the federal government, its leadership has to contend with the prospect of another shutdown weeks away, which may kick in after the current continuing resolution expires Jan. 15, 2014.

photoPiotr Kulesza, 46, Pathologist At Northwestern,
ECOG-ACRIN, Dies in Fall After Group MeetingPiotr Kulesza, a pathologist at Northwestern University Robert H. Lurie Cancer Center, who worked with the ECOG-ACRIN Cancer Research Group, died after a fall from a hotel balcony after attending the cooperative group’s semi-annual meeting. Kulesza was 46.
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In Brief
20131203_14 - Dec. 3, 2013
ISSUE 43 – NOV. 15, 2013PDF

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A new kind of clinical trial that will assign patients to therapy based on molecular characteristics of their disease is being launched by a coalition of government agencies, pharmaceutical companies, and a non-government organization.

The effort, called the lung cancer “Master Protocol,” is a phase II and phase III trial that would test five drugs, assigning patients to therapy based on tumor biomarkers.

photoVarmus: “We Are Shrinking Everything” To Keep Grant Numbers Level During Cuts

As NCI digs out after the two-week shutdown of the federal government, its leadership has to contend with the prospect of another shutdown weeks away, which may kick in after the current continuing resolution expires Jan. 15, 2014.

photoFDA Grants Accelerated Approval to Imbruvica

FDA granted an accelerated approval to Imbruvica (ibrutinib) for mantle cell lymphoma patients who have received at least one prior therapy. 

Imbruvica was approved four months after submission of its New Drug Application. The agent is sponsored by Pharmacyclics Inc.

20131203_10 - Dec. 3, 2013
ISSUE 42 – NOV. 8, 2013PDF

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Wicha to Leave Director’s Job at UMich

Conversation with The Cancer Letter: Max Wicha

After 27 years and six NCI cancer center support grants, Max Wicha announced he would step down as director of the University of Michigan Comprehensive Cancer Center.

“Frankly, my research is really going well now,” Wicha said in a Q&A with The Cancer Letter. “It’s in a very exciting phase in researching cancer stem cells. My lab has grown—and my work is now moving into the clinic, so I’m actually working with our clinical people to do clinical trials targeting cancer stem cells. 

“So the idea of five more years, or do I get to really focus on my research now? That was really the deciding factor. 

“So it’s time. Again, six core grants is quite a number.”

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More than 230,000 people—including 82 Texas state lawmakers—petitioned BioMarin Pharmaceutical Inc. to provide its investigational drug to an Austin attorney afflicted with stage IIIC ovarian cancer.

photoIn Brief

  • Lynne Penberthy named NCI DCCPS associate director for surveillance

  • Michele Bloch appointed chief of NCI Tobacco Control Research Branch

  • MD Anderson’s James Allison named 2013 Innovations Award winner in Bioscience by The Economist

  • European Commission approves Yervoy for first-line treatment of adult unresectable or metastatic melanoma

  • FDA approves generic Morphine Sulfate Injection

20131203_6 - Dec. 3, 2013
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