publication date: Jul. 5, 2019

NCI Trials NCI Trials for July

The National Cancer Institute Cancer Therapy Evaluation Program approved the following clinical research studies last month. 

For further information, contact the principal investigator listed.

 

Phase II – 10250

A Phase II Study of the PARP Inhibitor Olaparib in Combination with the DNA Damaging Agent Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma

Mayo Clinic Cancer Center LAO

Ingham, Matthew

646-317-7141

 

Phase II – 10292

DURVA+ : Evaluation of the Safety and Pharmacodynamics of Anti-PD-L1 Antibody MEDI4736 (Durvalumab) in Combination with Chemotherapy in Patients with Advanced Solid Tumors

National Cancer Institute LAO

Chen, A P

(240) 781-3320

 

Phase II/III – EA3161

A Phase II/III Randomized Study of Maintenance Nivolumab Versus Observation in Patients with Locally Advanced, Intermediate Risk HPV Positive OPCA

ECOG-ACRIN Cancer Research Group

Saba, Nabil F.

(404) 778-3126

 

Phase III – AALL1731

A Phase 3 Trial Investigating Blinatumomab (IND# 117467, NSC# 765986) in Combination with Chemotherapy in Patients with Newly Diagnosed Standard Risk or Down Syndrome B-Lymphoblastic Leukemia (B-ALL) and the Treatment of Patients with Localized B-Lymphoblastic Lymphoma (B-LLy)

Children’s Oncology Group

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