publication date: Oct. 12, 2018

Clinical Roundup

New ASTRO/ASCO/AUA guideline for early-stage prostate cancer supports use of shortened courses of radiation therapy

Three medical societies today issued a new clinical guideline for physicians treating men with early-stage prostate cancer using external beam radiation therapy.

Adoption of the guideline could make treatment shorter and more convenient for many patients with prostate cancer, the most common malignancy among American men. 

Developed by a panel of experts from the American Society for Radiation Oncology, American Society of Clinical Oncology and American Urological Association, the guideline recommends offering patients hypofractionated radiation therapy as an alternative to longer, conventional courses of radiation.

ASTRO, ASCO and AUA published the guideline in their respective journals, Practical Radiation Oncology, Journal of Clinical Oncology and The Journal of Urology.

“Conclusive evidence from several large, well-designed randomized trials now confirms that dose escalation can almost universally benefit men with early-stage prostate cancer who choose to manage their disease with external radiation,” said Howard Sandler, chair and professor of radiation oncology at Cedars-Sinai Medical Center and co-chair of the guideline panel. “Significant advances in treatment planning and delivery have enabled oncologists to deliver more powerful, life-saving doses of radiation in fewer visits and without compromising quality of life.” 

External beam radiation therapy is a standard definitive treatment option that confers outcomes equivalent to radical prostatectomy for men with localized prostate cancer. When EBRT is hypofractionated, patients receive larger radiation doses across fewer treatment sessions—typically completing treatment in four to five weeks, compared with eight to nine weeks for conventional radiation. Extremely hypofractionated courses, also known as ultrahypofractionation, stereotactic body radiation therapy or stereotactic ablative … Continue reading New ASTRO/ASCO/AUA guideline for early-stage prostate cancer supports use of shortened courses of radiation therapy

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