publication date: Feb. 16, 2018

Clinical Roundup

NCCN & ASCO provide joint guidance on side effects from checkpoint inhibitors

Guidelines developed collaboratively by the American Society of Clinical Oncology and the National Comprehensive Cancer Network offer clinicians recommendations for assessment and management of side effects related to immune checkpoint inhibitors.

There are already several checkpoint inhibitors approved by FDA for various cancers, including melanoma, Hodgkin lymphoma, and lung, liver, kidney, and bladder cancers. The use of checkpoint inhibitors is continuously expanding to more indications, along with the development of new checkpoint inhibitors and combinations.  

“With rapidly increasing use of immune checkpoint inhibitors, it is imperative that clinicians are knowledgeable about their unique toxicity profiles,” Clifford Hudis, ASCO CEO, said in a statement. “These new guidelines from ASCO and NCCN will help our community continue to provide the highest quality of care to all patients as they incorporate these agents into routine care.”

There are already several checkpoint inhibitors approved by FDA for various cancers, including melanoma, Hodgkin lymphoma, and lung, liver, kidney, and bladder cancers. And the use of checkpoint inhibitors is continuously expanding to more indications, along with the development of new checkpoint inhibitors and combinations.

“The real winners here are patients whose health care teams now have high quality, collaborative guidelines from ASCO and NCCN to minimize treatment toxicity and optimize outcomes,” Robert Carlson, NCCN CEO, said in a statement. “While novel immunotherapies allow for life-extending therapy for selected forms of cancer, their success is associated with potentially substantial toxicity. These side effects are different from other forms of anticancer therapy and require rapid and appropriate recognition and treatment. NCCN has been pleased to collaborate with ASCO on developing strategies … Continue reading NCCN & ASCO provide joint guidance on side effects from checkpoint inhibitors

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