publication date: Mar. 31, 2016

NCI CTEP-Approved Trials for the Month of March


The National Cancer Institute Cancer Therapy Evaluation Program approved the following clinical research studies last month. For further information, contact the principal investigator listed.


Phase I

10004: A Phase I Study of Subcutaneous Recombinant Human IL-15 (S.C. Rhil-15) and Alemtuzumab for Patients with Refractory or Relapsed Chronic and Acute Adult T-Cell Leukemia (ATL). NCI Center for Cancer Research; Waldmann, Thomas Alexander. (301) 496-6656


9882: Phase I and Pharmacology Study of Oral 5-Iodo-2-Pyrimidinone-2’- Deoxyribose (IPdR) as a Prodrug for IUdR-Mediated Tumor Radiosensitization in Gastrointestinal Cancers. Rhode Island Hospital; Kinsella, Timothy James. (401) 444-6203


Phase II

AOST1521: A Phase 2 Study of GPNMB-Targeted Antibody-Drug Conjugate, CDX-011 (Glembatumumab Vedotin, CR011-vcMMAE; IND# 128248, NSC# 763737), in Recurrent or Refractory Osteosarcoma. Children’s Oncology Group; Kopp, Lisa M. (520) 626-2021


Other Phases

AALL15B2-Q: Use of DNA Methylation Assessment by xMELP for Prognosis in Pediatric Patients with T-ALL. Children’s Oncology Group; Wertheim, Gerald. (267) 970-5918


AALL15B7-Q: Role of the MAPK/ERK Pathway in Relapsed Pediatric B-Lymphoblastic Leukemia: Prognostic Implications and Potential for Targeted Therapy. Children’s Oncology Group; Carroll, William L. (212) 263-9947


ANHL15B1-Q: B-Lineage Lymphoblastic Lymphoma … Continue reading CCL March – NCI CTEP-Approved Trials for the Month of March

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