publication date: Mar. 4, 2016

National Academy of Medicine Publishes Report on Categorizing Different Ovarian Cancers 


Ovarian cancer should not be categorized as a single disease, but as many different cancers involving the ovary, according to a report published by the National Academy of Medicine.

Questions remain on how and where various ovarian cancers arise, said the report that also presents research opportunities for reducing the number of women who are diagnosed with or die from ovarian cancers. Roughly two-thirds of women are diagnosed at an advanced stage when the cancer has already spread beyond the ovary, of which less than 30 percent survive past five years. The report was also sponsored by the Centers for Disease Control and Prevention.

“When we look at ovarian cancers at the molecular level, we can see that many of these tumors arise in other organs or cell types and then metastasize to the ovary,” said report co-author Kunle Odunsi, deputy director and chair of gynecologic oncology at Roswell Park Cancer Institute.

“This is a striking finding that changes our fundamental understanding of ovarian cancer, but it also underscores how much we have yet to learn about ovarian cancer subtypes and their progression.”

Furthermore, researchers do not have a complete understanding of how each subtype of ovarian cancer progresses, the report said. The committee publishing the report recommended that researchers and funding organizations design and prioritize research agendas to take into account the different ovarian cancer subtypes, and a top priority in research should be to determine the cellular origins and how the disease develops.

A family … Continue reading 42-09 National Academy of Medicine Publishes Report on Categorizing Different Ovarian Cancers

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